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Network of Extracellular Traps in the Pathogenesis of Sterile Chronic Inflammatory Diseases: Role of Oxidative Stress and Potential Clinical Applications

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; ()

Significance: Extracellular traps (ETs) represent structured frameworks that comprised DNA embellished with histones and granular proteins extruded by......

Reactive Oxygen Species as Mediators of Disease Progression and Therapeutic Response in Colorectal Cancer

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 39 (1-3)

Significance: Reactive oxygen species (ROS) are critical to normal cellular function with redox homeostasis achieved by balancing ROS production with ......

Meta-Analysis of Antioxidant Mutants Reveals Common Alarm Signals for Shaping Abiotic Stress-Induced Transcriptome in Plants

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; ()

Aims: Reactive oxygen species (ROS) are key regulators of plant growth, development, and stress tolerance. Stress-induced changes in ROS levels trigge......

Insights Into Antioxidant Strategies to Counteract Radiation-Induced Male Infertility

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; ()

Significance: Radiotherapy, which employs ionizing radiation to destroy or prevent the multiplication of tumor cells, has been increasingly used in th......

Ferroptosis As Ultimate Target of Cancer Therapy

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 39 (1-3)

Significance: The significance of ferroptosis in cancer therapeutics has now been unveiled. Specific ferroptosis inducers are expected as a promising ......

Potentiation of Adipogenesis by Reactive Oxygen Species Is a Unifying Mechanism in the Proadipogenic Properties of Bisphenol A and Its New Structural Analogues

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; ()

Aims: Structural analogues of bisphenol A (BPA), including bisphenol S (BPS) and bisphenol F (BPF), are emerging environmental toxicants as their pres......

Role of Gasotransmitters in Inflammatory Edema

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; ()

Significance: Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) are, to date, the identified members of the gasotransmitter family, ......

Nicotinamide Adenosine Dinucleotide Phosphate Oxidase-Mediated Signaling in Cardiac Remodeling

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 38 (4)

Significance: Reactive oxygen species (ROS) play a key role in the pathogenesis of cardiac remodeling and the subsequent progression to heart failure ......

The MarR/DUF24-Family QsrR Repressor Senses Quinones and Oxidants by Thiol Switch Mechanisms in Staphylococcus aureus

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 38 (13)

Aims: The MarR/DUF24-family QsrR and YodB repressors control quinone detoxification pathways in Staphylococcus aureus and Bacillus subtilis. In S. aur......

Redox Modulation of Mitochondrial Proteins in the Neurotoxicant Models of Parkinson's Disease

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 38 (10-12)

Significance: Mitochondrial proteins regulate the oxidative phosphorylation, cellular metabolism, and free radical generation. Redox modulation alters......

H2S-Generating Cytosolic L-Cysteine Desulfhydrase and Mitochondrial D-Cysteine Desulfhydrase from Sweet Pepper (Capsicum annuum L.) Are Regulated During Fruit Ripening and by Nitric Oxide

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 39 (1-3)

Aims: Pepper fruit is a horticultural product worldwide consumed that has great nutritional and economic relevance. Besides the phenotypical changes t......

Mitochondrial Dysfunction and Mitophagy in Type 2 Diabetes: Pathophysiology and Therapeutic Targets

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 39 (4-6)

Significance: Type 2 diabetes mellitus, which is related to oxidative stress and mitochondrial dysfunction, is one of the most prevalent diseases in t......

Actions of Thiols, Persulfides, and Polysulfides as Free Radical Scavenging Antioxidants

期刊: ANTIOXIDANTS & REDOX SIGNALING, 2023; 39 (10-12)

Significance: The essential roles of thiol compounds as redox signaling mediators and protectors have been established. Recently, the roles of persulf......

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