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Recent advances in neuroanatomy: the myotome update

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; 94 (8)

The myotome of a muscle is the basis for diagnosing spinal and peripheral nerve disorders. Despite its critical importance in clinical neurology, myot......

Anti-Argonaute antibodies as a potential biomarker in NMOSD

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; 94 (9)

Background and objectivesNeuromyelitis optica spectrum disorders (NMOSDs) are a group of diseases mainly characterised by recurrent optic neuritis and......

Spinal cord lesions and brain grey matter atrophy independently predict clinical worsening in definite multiple sclerosis: a 5-year, multicentre study

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; 94 (1)

Objectives To evaluate the combined contribution of brain and cervical cord damage in predicting 5-year clinical worsening in a multicentre cohort of ......

Longitudinal characterisation of B and T-cell immune responses after the booster dose of COVID-19 mRNA-vaccine in people with multiple sclerosis using different disease-modifying therapies

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; 94 (4)

BackgroundThe decline of humoral response to COVID-19 vaccine led to authorise a booster dose. Here, we characterised the kinetics of B-cell and T-cel......

Association of choroid plexus volume with motor symptoms and dopaminergic degeneration in Parkinson's disease

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; ()

BackgroundThe choroid plexus (CP) is involved in the clearance of harmful metabolites from the brain, as a part of the glymphatic system. This study a......

Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal damage

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; ()

BackgroundMultiple sclerosis (MS) and presymptomatic axonal injury appear to develop only after an Epstein-Barr virus (EBV) infection. This associatio......

Unravelling the influence of affective stimulation on functional neurological symptoms: a pilot experiment examining potential mechanisms

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; ()

Background Differences in affective processing have previously been shown in functional neurological disorder (FND); however, the mechanistic relevanc......

Clinical phenotypic diversity of NOTCH2NLC-related disease in the largest case series of inherited peripheral neuropathy in Japan

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; 94 (8)

BackgroundNOTCH2NLC GGC repeat expansions have been associated with various neurogenerative disorders, including neuronal intranuclear inclusion disea......

Genotype-phenotype correlation and treatment effects in young patients with GNAO1-associated disorders

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; 94 (10)

BackgroundPatients carrying pathogenic variants in GNAO1 often present with early-onset central hypotonia and global developmental delay, with or with......

Evolution of brain MRI lesions in paediatric myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and its relevance to disease course

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; ()

Background Lesion resolution is often observed in children with myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD), and asymptoma......

Circadian rhythm of ischaemic core progression in human stroke

期刊: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2023; 94 (1)

Introduction Experimental stroke studies suggest an influence of the time of day of stroke onset on infarct progression. Whether this holds true after......

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