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Evaluation of Cognitive and Physical Function Among Older Adults by Their Physical Activity: A Cross-Sectional Kasama Study, Japan

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 96 (4)

Background: The amyloid-beta(1-42) (A beta(42)) level is a biomarker that is widely used to evaluate individual cognitive dysfunction early in neurode......

Comparison of Brain Amyloid Deposition and Cortical Glucose Metabolism Between Clinic- and Community-Based Cohort

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 95 (1)

Background: The differences in positron emission tomography (PET) imaging among older adults with mild cognitive impairment (MCI), according to the re......

Clinical Quality Indicators for Monitoring Hospitalizations Among Older People with Dementia Accessing Aged Care Services

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 96 (4)

Background: There is a need for clinical quality indicators (CQIs) that can be applied to dementia quality registries to monitor care outcomes for peo......

The Association of Life Stress with Subsequent Brain and Cognitive Reserve in Middle-Aged Women

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 93 (1)

Background: Cognitive and brain reserve refer to individual differences that allow some people to better withstand brain pathology than others. Althou......

A Novel c.800G>C Variant of the ITM2B Gene in Familial Korean Dementia

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 93 (2)

Mutations in ITM2B have been reported to be associated with several familial dementias, such as Familial British dementia and familial Danish dementia......

Subtle Differences in Cognition in 70-Year-Olds with Elevated Cerebrospinal Fluid Neurofilament Light and Neurogranin: A H70 Cross-Sectional Study

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 91 (1)

Background: Most research on cerebrospinal fluid (CSF) neurofilament light protein (NfL) as a marker for neurodegeneration and neurogranin (Ng) for sy......

Memory Outcome in Prodromal and Mild Dementia with Lewy Bodies and Alzheimer's Disease: A Longitudinal Study

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 94 (1)

Background: Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are likely to induce memory impairments from the prodromal stage but, to our ......

Respectful Caring for the Agitated Elderly (ReCAGE): A Multicentre, Prospective, Observational Study to Evaluate the Effectiveness of Special Care Units for People with Dementia

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 96 (3)

Background: Behavioral and psychological symptoms of dementia (BPSD) bring complexity in the clinical management of people with dementia; therefore, i......

Neurofunctional Correlates of Activities of Daily Living in Patients with Posterior Cortical Atrophy

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 93 (1)

Background: Research on posterior cortical atrophy (PCA) has focused on cognitive decline, especially visual processing deficits. However, few studies......

The Dual Role of Astrocyte-Derived Exosomes and Their Contents in the Process of Alzheimer's Disease

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 91 (1)

Millions of patients worldwide are affected by Alzheimer's disease (AD), and the number of patients with AD is increasing. However, current treatment ......

Subjective Cognitive Decline Is Associated with Health-Related Quality of Life in the Middle-Aged to Elderly Population

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 91 (1)

Background: Subjective cognitive decline (SCD) is considered to be a preliminary stage of dementia, and its prevalence is increasing with age. Objecti......

Clinical Evaluation of Cerebrospinal Fluid p217tau and Neurofilament Light Chain Levels in Patients with Alzheimer's Disease or Other Neurological Diseases

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 96 (4)

Background: The cerebrospinal fluid (CSF) levels of tau phosphorylated at threonine 217 (p217tau) or 181 (p181tau), and neurofilament light chain (NfL......

Increased Resolution of Structural MRI at 3T Improves Estimation of Regional Cortical Degeneration in Individual Dementia Patients Using Surface Thickness Maps

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 95 (3)

Background: Objective measurement of regional cortical atrophy in individual patients would be a highly desirable adjunct for diagnosis of degenerativ......

Features of Cerebral Small Vessel Disease Contributes to the Differential Diagnosis of Alzheimer's Disease

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 91 (2)

Background: Cerebral small vessel disease (CSVD), which comprises the typical features of white matter hyperintensity (WMH) and Vichor-Robin spaces (V......

The Diagnostic Potential of Circulating Autoantibodies to Amyloid-β in Alzheimer's Disease

期刊: JOURNAL OF ALZHEIMERS DISEASE, 2023; 94 (2)

Background: The profile of naturally occurring antibodies to amyloid-beta (NAbs-A beta) is altered in patients with Alzheimer's disease (AD). However,......

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