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Treponema pallidum detection in lesion and non-lesion sites in men who have sex with men with early syphilis: a prospective, cross-sectional study

期刊: LANCET INFECTIOUS DISEASES, 2021; 21 (9)

Background Syphilis transmission is increasing, and precisely how Treponema pallidum is transmitted sexually from person to person is unclear. We aime......

Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy adults aged 60 years and older: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial

期刊: LANCET INFECTIOUS DISEASES, 2021; 21 (6)

Background A vaccine against COVID-19 is urgently needed for older adults, in whom morbidity and mortality due to the disease are increased. We aimed ......

Immunogenicity and safety of simplified vaccination schedules for the CYD-TDV dengue vaccine in healthy individuals aged 9-50 years (CYD65): a randomised, controlled, phase 2, non-inferiority study

期刊: LANCET INFECTIOUS DISEASES, 2021; 21 (4)

Background Three doses of the licensed tetravalent dengue vaccine CYD-TDV (Dengvaxia, Sanofi Pasteur, Lyon France) are immunogenic and effective again......

The potential health and economic value of SARS-CoV-2 vaccination alongside physical distancing in the UK : a transmission model-based future scenario analysis and economic evaluation

期刊: LANCET INFECTIOUS DISEASES, 2021; 21 (7)

Background In response to the COVID-19 pandemic, the UK first adopted physical distancing measures in March, 2020. Vaccines against SARS-CoV-2 became ......

Appropriateness of antibiotic prescriptions in ambulatory care in China: a nationwide descriptive database study

期刊: LANCET INFECTIOUS DISEASES, 2021; 21 (6)

Interpretation Inappropriate antibiotic prescribing was highly prevalent nationwide in China. Over half of the antibiotic prescriptions were inappropr......

Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD-based protein subunit vaccine (ZF2001) against COVID-19 in adults: two randomised, double-blind, placebo-controlled, phase 1 and 2 trials

期刊: LANCET INFECTIOUS DISEASES, 2021; 21 (8)

Background Although several COVID-19 vaccines have been developed so far, they will not be sufficient to meet the global demand. Development of a wide......

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