期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 425 ()
Triptolide (TP), a primary bioactive ingredient isolated from the traditional Chinese herbal medicine Tripterygium wilfordii Hook. F. (TWHF), has attr......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 418 ()
Copper (Cu) is considered as an essential trace element for living organisms. However, over-exposure to Cu can lead to adverse health effects on human......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 422 ()
Many researchers have studied the relationship between lead (Pb) and testis injury, but the underlying mechanisms are still unknown. The participation......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 427 ()
Bacterial superantigens potently activate conventional T-cells to induce massive cytokine production and mediate tumor cell death. To engineer superan......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 418 ()
The clinical use of cisplatin are limited due to its drug resistance. Thus, it is urgent to find effective combination therapy that sensitizes tumor c......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 419 ()
Lung cancer is considered the main cause of cancer mortality worldwide. Osimertinib, a third-generation EGFRTKI, has been approved and administrated f......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 419 ()
Hesperetin (HSP) has excellent biological activities with poor water solubility which limits its clinical development. In this study, we successfully ......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 427 ()
Pharmacological postconditioning (PPC), drug intervention before or during the early minutes of reperfusion, could stimulate cardioprotection as ische......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 419 ()
Phthalates as plasticizers are widely used in many consumer products. Dipentyl phthalate (DPeP) is one of phthalates. However, there are currently few......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 421 ()
Cadmium (Cd) can induce ovarian injury by microRNAs (miRNAs), however, the molecular mechanism of miRNAs after Cd exposure have not known. In this stu......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 423 ()
Bongkrekic acid (BKA) produced by pseudomonas cocovenenans is a deadly toxin, and is mainly found in spoiled or fermented foods. However, less is know......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 420 ()
Baicalein is a purified flavonoid that exhibits anticancer effects in hepatocellular carcinoma (HCC). However, its underlying molecular mechanisms rem......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 417 ()
Heat Shock Protein 90 (Hsp90) is frequently upregulated in many cancers, and its inhibition simultaneously blocks multiple signaling pathways, resulti......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 420 ()
Isorhynchophylline (IRN) is an alkaloid with anti-inflammatory and anti-oxidative activities in cardiovascular and brain diseases, but its role in par......
期刊： TOXICOLOGY AND APPLIED PHARMACOLOGY, 2021; 422 ()
Sodium valproate (SVP) is one of the most commonly prescribed antiepileptic drugs. However, SVP is known to induce hepatotoxicity, which limits its cl......
