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Metastasis suppressor 1 acts as a tumor suppressor by inhibiting epithelial-to-mesenchymal transition in triple-negative breast cancer

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Objective: This study aimed to analyze the function of metastasis suppressor 1 (MTSS1) in triple negative breast cancer (TNBC). Methods: MTSS1 express......

Immunoscore system combining CD8 and PD-1/PD-L1: A novel approach that predicts the clinical outcomes for cervical cancer

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Purpose: Immunoscore was established to evaluate the prognosis of cancer patients. However, the feasibility of Immunoscore for the prognosis of cervic......

Lower circulating adiponectin is associated with higher risk of renal cell carcinoma: A meta-analysis

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Background: Changes in circulating adiponectin have been related to the risks of various cancers. However, the association between circulating adipone......

Regulating of cell cycle progression by the lncRNA CDKN2B-AS1/miR-324-5p/ROCK1 axis in laryngeal squamous cell cancer

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Objective: To evaluate the function of long non-coding RNA ANRIL (CDKN2B-AS1) in laryngeal squamous cell cancer (LSCC), and to explore the underlying ......

HNF-1 binding point mutation of the AFP gene promotes cirrhosis in post-menopausal women

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Objective: alpha-fetoprotein (AFP) expression is activated during the embryonic stage or hepatocellular carcinogenesis, so it is presumed that AFP is ......

High expression of IGBP1 correlates with poor prognosis in esophageal squamous cell carcinoma

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Background: Immunoglobulin binding protein 1 (IGBP1) is an important signal transduction regulator that mediates various functions. However, its expre......

Comparing prognostic values of the 7th and 8th editions of the American Joint Committee on Cancer TNM staging system for gastric cancer

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Background and Aim: Our aim was to compare the prognostic value of the American Joint Committee on Cancer (AJCC) 7th and 8th editions staging systems ......

Cytotoxin-associated gene A increases carcinogenicity of helicobacter pylori in colorectal adenoma

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Objective: This study aimed to investigate the correlation of Helicobacter pylori (Hp) infection with disease risk and severity of colorectal adenoma,......

Long non-coding RNA AGER-1 inhibits colorectal cancer progression through sponging miR-182

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Objective: Abundant evidence has illustrated that long non-coding RNA (lncRNA) plays a vital role in the regulation of tumor development and progressi......

Polymorphisms of a novel long non-coding RNA RP11-108K3.2 with colorectal cancer susceptibility and their effects on its expression

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (1)

Background: RP11-108K3.2 was recently identified as a novel long non-coding RNA (lncRNA) transcript, and several single nucleotide polymorphisms (SNPs......

A-kinase interacting protein 1, a potential biomarker associated with advanced tumor features and CXCL1/2 in prostate cancer

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (2)

Objective: This study aimed to investigate the correlation of A-kinase interacting protein 1 (AKIP1) with chemokine (C-X-C motif) ligand 1 (CXCL1) and......

Diagnostic Value of Albumin to Fibrinogen Ratio in Cervical Cancer

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (2)

Background: Albumin to fibrinogen ratio (AFR) play a crucial role in the progression and prognosis of many malignant tumors. This study aimed to compr......

Upregulation of far upstream element-binding protein 1 (FUBP1) promotes tumor proliferation and unfavorable prognosis in tongue squamous cell carcinoma

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (2)

Background: A well-known transcriptional regulator of the proto-oncogene c-Myc, far-upstream element (FUSE) binding protein 1 (FUBP1) has been demonst......

The association ofHelicobacter pyloriCagA EPIYA motifs and vacA genotypes with homologous recombination repair markers during the gastric precancerous cascade

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (2)

Background: Helicobacter pylori-induced DNA damage and impaired homologous recombination repair are vital molecular mechanisms for gastric cancer, whi......

Circulating lncRNAs as noninvasive biomarkers in bladder cancer: A diagnostic meta-analysis based on 15 published articles

期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, 2020; 35 (2)

Objective Owing to inconsistency between reports, a meta-analysis was designed to appraise the clinical implications of long non-coding RNAs (lncRNAs)......

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