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LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (3)

Abdominal aortic aneurysm (AAA) is a progressive chronic dilatation of the abdominal aorta without effective medical treatment. This study aims to cla......

Knockdown of TPT1-AS1 inhibits cell proliferation, cell cycle G1/S transition, and epithelial-mesenchymal transition in gastric cancer

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (1)

Long non-coding RNAs are considered to be critical regulators of tumor progression. Tumor protein translationally controlled 1 ant isense RNA 1 (TPT1-......

Cryptic t(15;17) acute promyelocytic leukemia with a karyotype of add(11)(p15) and t(13;20) - A case report with a literature review

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (2)

Most acute promyelocytic leukemias (APL) are characterized by reciprocal translocations t(1.537)(q22;21), which results in the fusion of the promyeloc......

Stomach-specific c-Myc overexpression drives gastric adenoma in mice through AKT/mammalian target of rapamycin signaling

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (4)

Gastric cancer (GC) is one of the most common malignant cancers in the world. c-Myc, a well known oncogene, is commonly amplified in many cancers, inc......

Alectinib and lorlatinib function by modulating EMT-related proteins and MMPs in NSCLC metastasis

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (3)

Most advanced non-small cell lung cancer (NSCLC) patients are accompanied by brain metastasis which is the major cause of increased mortality. The fus......

Quantitative detection of circulating MT-ND1 as a potential biomarker for colorectal cancer

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (5)

Liquid biopsy represents a diagnostic and monitoring tool and the circulating cell-free mitochondrial DNA (mtDNA) plays a vital role in tumor diagnosi......

A three-dimensional computed tomography study to determine the ideal method for fluoroscopically-guided bone marrow aspiration from the iliac crest

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (3)

Bone marrow aspiration (BMA) through the iliac crest is potentially unsafe due to the vicinity of neurovascular structures in the greater sciatic notc......

The role of WDR76 protein in human diseases

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (5)

The WD40 repeat (WDR) domain is one of the most abundant protein interaction domains in the human proteome. More than 360 protein interaction domains ......

The association between serine hydroxymethyl transferase 1 gene hypermethylation and ischemic stroke

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (4)

This study aimed to determine the correlation between serine hydroxymethyl transferase (SHMT1) gene methylation and ischemic stroke. A total of 202 ag......

Circ-RNF13, as an oncogene, regulates malignant progression of HBV-associated hepatocellular carcinoma cells and HBV infection through ceRNA pathway of circ-RNF13/miR-424-5p/TGIF2

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (5)

Circular RNA RNF13 (circ-RNF13; ID: hsa_circ_0067717) is newly identified to be abnormally upregulated in hepatitis B virus (HBV)-associated hepatocel......

Development and validation of a SEER-based prognostic nomogram for cervical cancer patients below the age of 45 years

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (5)

In this study, we established a nomogram for the prognostic prediction of patients with early-onset cervical cancer (EOCC) for both overall survival (......

Development and validation of a ferroptosis-related lncRNAs prognosis signature in colon cancer

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (5)

Ferroptosis is a form of iron-dependent programmed cell death. Regulate ferroptosis in tumor cells is a novel treatment modality. The present study ai......

Progress in research on childhood T-cell acute lymphocytic leukemia, Notch1 signaling pathway, and its inhibitors: A review

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (2)

Childhood leukemia is cancer that seriously threatens the life of children in China. Poor sensitivity to chemotherapy and susceptibility to drug resis......

Raloxifene inhibits the overexpression of TGF-beta 1 in cartilage and regulates the metabolism of subchondral bone in rats with osteoporotic osteoarthritis

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (3)

Overexpression of transforming growth factor-beta 1 (TGF-beta 1) and subchondral bone remodeling play key roles in osteoarthritis (OA). Raloxifene (RA......

Recent advances of targeted therapy in relapsed/refractory acute myeloid leukemia

期刊: BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (4)

Despite advances in the understanding of disease pathobiology, treatment for relapsed or refractory acute myeloid leukemia (R/R AML) remains challengi......

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