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Utility of Human In Vitro Data in Risk Assessments of Influenza A Virus Using the Ferret Model

期刊: JOURNAL OF VIROLOGY, 2023; 97 (1)

Both in vitro and in vivo models are employed for assessing the pandemic potential of novel and emerging influenza A viruses in laboratory settings, b......

Virology under the Microscope-a Call for Rational Discourse

期刊: JOURNAL OF VIROLOGY, 2023; ()

Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology re......

All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein

期刊: JOURNAL OF VIROLOGY, 2023; 97 (3)

The nsp1 of SARS-CoV-2 is a multifunctional protein that modifies the intracellular environment for the needs of viral replication. It is responsible ......

Isolation of an Ecotropic Porcine Endogenous Retrovirus PERV-C from a Yucatan SLAD/D Inbred Miniature Swine

期刊: JOURNAL OF VIROLOGY, 2023; 97 (3)

Xenotransplantation may compensate the limited number of human allografts for transplantation using pigs as organ donors. Porcine endogenous retroviru......

Porcine Enteric Alphacoronavirus Entry through Multiple Pathways (Caveolae, Clathrin, and Macropinocytosis) Requires Rab GTPases for Endosomal Transport

期刊: JOURNAL OF VIROLOGY, 2023; 97 (4)

Emerging and reemerging coronaviruses cause severe human and animal epidemics worldwide. PEAV is the first bat-like coronavirus to cause infection in ......

Evaluation of the Interactions between Mumps Virus and Guinea Pig

期刊: JOURNAL OF VIROLOGY, 2023; 97 (4)

Mumps is a highly contagious viral disease that can be prevented by vaccination. In the last decade, we have encountered repeated outbreaks of mumps i......

The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1

期刊: JOURNAL OF VIROLOGY, 2023; 97 (4)

Stimulator of interferon (IFN) genes (STING) was recently pinpointed as an antiviral innate immune factor during the infection of RNA viruses. Porcine......

The Small GTPase Rab14 Regulates the Trafficking of Ceramide from Endoplasmic Reticulum to Golgi Apparatus and Facilitates Classical Swine Fever Virus Assembly

期刊: JOURNAL OF VIROLOGY, 2023; 97 (5)

Classical swine fever virus (CSFV) is a highly pathogenic RNA virus belonging to the Flaviviridae family that can cause deadly classical swine fever (......

HIV-1 3′-Polypurine Tract Mutations Confer Dolutegravir Resistance by Switching to an Integration-Independent Replication Mechanism via 1-LTR Circles

期刊: JOURNAL OF VIROLOGY, 2023; 97 (5)

Several recent studies indicate that mutations in the human immunodeficiency virus type 1 (HIV-1) 3 ' polypurine tract (3 ' PPT) motif can reduce sens......

The SETD2 Methyltransferase Supports Productive HPV31 Replication through the LEDGF/CtIP/Rad51 Pathway

期刊: JOURNAL OF VIROLOGY, 2023; 97 (5)

The human papillomavirus (HPV) life cycle takes place in the stratified epithelium, with the productive phase being activated by epithelial differenti......

African Swine Fever Virus H240R Protein Inhibits the Production of Type I Interferon through Disrupting the Oligomerization of STING

期刊: JOURNAL OF VIROLOGY, 2023; 97 (9)

African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and acute hemorrhagic viral disease with a high mortalit......

Conformations of Human Immunodeficiency Virus Envelope Glycoproteins in Detergents and Styrene-Maleic Acid Lipid Particles

期刊: JOURNAL OF VIROLOGY, 2023; 97 (6)

The human immunodeficiency virus (HIV) envelope glycoproteins (Envs) in the viral membrane mediate virus entry into the host cell and are targeted by ......

Neuroinvasive Flavivirus Pathogenesis Is Restricted by Host Genetic Factors in Collaborative Cross Mice, Independently of Oas1b

期刊: JOURNAL OF VIROLOGY, 2023; 97 (7)

Neuroinvasive flaviviruses, such as WNV, JEV, and POWV, are transmitted to humans by mosquitoes or ticks and can cause neurologic diseases, such as en......

SLF2 Interacts with the SMC5/6 Complex to Direct Hepatitis B Virus Episomal DNA to Promyelocytic Leukemia Bodies for Transcriptional Repression

期刊: JOURNAL OF VIROLOGY, 2023; 97 (7)

Chronic HBV infection remains a major public health problem worldwide. Current antiviral treatments rarely cure the infection, as they cannot clear th......

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