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Risk factors for metabolic bone disease among preterm infants less than 32weeks gestation with Bronchopulmonary dysplasia

期刊: BMC PEDIATRICS, 2021; 21 (1)

BackgroundBronchopulmonary dysplasia (BPD) infants present an increased incidence of metabolic bone disease (MBD), but it is unknown which factors con......

Age related gene DST represents an independent prognostic factor for MYCN non-amplified neuroblastoma

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background MYCN amplification and age are two critical prognostic factors of pediatric neuroblastoma. Previously, we had revealed the prognosis of MYC......

Neonatal hypoxic-ischemic encephalopathy diagnosis and treatment: a National Survey in China

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background: Neonatal hypoxic-ischemic encephalopathy (HIE) affects as many as 100,000 infants each year in China. Therapeutic hypothermia reduces HIE ......

Characteristics of childhood allergic diseases in outpatient and emergency departments in Shanghai, China, 2016-2018: a multicenter, retrospective study

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background The prevalence of allergic diseases (ADs), such as asthma and allergic rhinitis (AR), is increasing worldwide in both adults and children. ......

Clinical and genetic analysis of a case with centronuclear myopathy caused by SPEG gene mutation: a case report and literature review

期刊: BMC PEDIATRICS, 2021; 21 (1)

BackgroundCentronuclear myopathy (CNM), a subtype of congenital myopathy (CM), is a group of clinical and genetically heterogeneous muscle disorders. ......

A pilot study to evaluate the role of circulation CD4(+) CCR6(+) CRTh2(+) cell in predicting risk of asthma in wheezing children

期刊: BMC PEDIATRICS, 2021; 21 (1)

BackgroundWheezing is common in younger children and often related to viral infection. It is lack of reliable indicators for asthma prediction.Objecti......

Relationship between maternal vitamin D status in the first trimester of pregnancy and maternal and neonatal outcomes: a retrospective single center study

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background This study aimed to investigate the relationship between maternal serum vitamin D status in the first trimester of pregnancy and maternal a......

Clinical characteristics and prognostic factors of hepatoblastoma in 316 children aged under 3 years - a 14-year retrospective single-center study

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background The aim of the present study was to summarize the clinical characteristics of in children aged under 3 years and analyze the related factor......

Th cytokine profile in childhood-onset systemic lupus erythematosus

期刊: BMC PEDIATRICS, 2021; 21 (1)

BackgroundChildhood-onset systemic lupus erythematosus (cSLE) is a kind of chronic inflammatory disease characterized by a highly abnormal immune syst......

Prevalence and risk factors for antibiotic utilization in Chinese children

期刊: BMC PEDIATRICS, 2021; 21 (1)

BackgroundAntibiotic resistance poses a significant threat to public health globally. Irrational utilization of antibiotics being one of the main reas......

Paediatric preoperative sedation practices in tertiary maternity and children's hospitals in China: a questionnaire survey

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background Preoperative anxiety is a common problem in the paediatric population, and several studies have reported that it is related to adverse even......

The clinical value of passive leg raising plus ultrasound to predict fluid responsiveness in children after cardiac surgery

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background There are few non-invasive monitoring methods that can reliably predict fluid responsiveness (FR) in children. Here, we interrogate the val......

Updated analysis of pediatric clinical studies registered in ClinicalTrials.gov, 2008-2019

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background: Since the national clinical trials registry (ClinicalTrials.gov) launched in February 2000, more than 360, 000 research studies in the Uni......

Two novel mutations in TCIRG1 induced infantile malignant osteopetrosis: a case report

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background Infantile malignant osteopetrosis (IMO) is a rare autosomal recessive disease characterized by a higher bone density in bone marrow caused ......

The association between ambient air pollution and birth defects in five major ethnic groups in Liuzhou, China

期刊: BMC PEDIATRICS, 2021; 21 (1)

Background: Studies suggest that exposure to ambient air pollution during pregnancy may be associated with increased risks of birth defects (BDs), but......

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