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Infectious bronchitis virus: Identification of Gallus gallus APN high-affinity ligands with antiviral effects

期刊: ANTIVIRAL RESEARCH, 2021; 186 ()

Infectious bronchitis virus (IBV) is a coronavirus, causes infectious bronchitis (IB) with high morbidity and mortality, and gives rise to huge econom......

Methodology-dependent performance of serum HBV RNA in predicting treatment outcomes in chronic hepatitis B patients

期刊: ANTIVIRAL RESEARCH, 2021; 189 ()

Background: Whether different serum HBV RNA detection assays can consistently predict treatment outcomes in patients with chronic hepatitis B remains ......

E3 ubiquitin ligase TRIM21 restricts hepatitis B virus replication by targeting HBx for proteasomal degradation

期刊: ANTIVIRAL RESEARCH, 2021; 192 ()

As a cytosol ubiquitin ligase and antibody receptor, Tripartite motif-containing 21 (TRIM21) has been reported to mediate the restriction of hepatitis......

Inhibition of coronavirus infection by a synthetic STING agonist in primary human airway system

期刊: ANTIVIRAL RESEARCH, 2021; 187 ()

The newly emerged severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) coronavirus initiated a pneumonia outbreak (COVID-19) that rapidly spre......

Construction and evaluation of DNA vaccine encoding Ebola virus glycoprotein fused with lysosome-associated membrane protein

期刊: ANTIVIRAL RESEARCH, 2021; 193 ()

Ebola virus (EBOV) of the genus Ebolavirus belongs to the family Filoviridae, which cause disease in both humans and non-human primates. Zaire Ebola v......

Inhibition of herpes simplex virus 1 by cepharanthine via promoting cellular autophagy through up-regulation of STING/TBK1/P62 pathway

期刊: ANTIVIRAL RESEARCH, 2021; 193 ()

Cepharanthine (CEP), a naturally occurring isoquinoline alkaloid extracted from the genus CEP of the Tetrandrine family, was reported to possess many ......

A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection

期刊: ANTIVIRAL RESEARCH, 2021; 189 ()

Coinfection of hepatitis B virus (HBV) and hepatitis C virus (HCV) may result in severe liver disease and frequent progression to cirrhosis and hepato......

A cell-based assay to discover inhibitors of SARS-CoV-2 RNA dependent RNA polymerase

期刊: ANTIVIRAL RESEARCH, 2021; 190 ()

Antiviral therapeutics is one effective avenue to control and end this devastating COVID-19 pandemic. The viral RNA-dependent RNA polymerase (RdRp) of......

Baseline serum hepatitis B core antibody level predicts HBeAg seroconversion in patients with HBeAg-positive chronic hepatitis B after antiviral treatment

期刊: ANTIVIRAL RESEARCH, 2021; 193 ()

Antibody to hepatitis B core antigen (anti-HBc) is one of the most classical serological markers of HBV infection. This study aimed to investigate the......

Cinnamic acid inhibits Zika virus by inhibiting RdRp activity

期刊: ANTIVIRAL RESEARCH, 2021; 192 ()

In recent years, Zika virus (ZIKV), which causes severe diseases such as congenital microcephaly and Guillain-Barr 'e syndrome, bringing serious harm ......

Development of cell culture infectious clones for hepatitis C virus genotype 1b and transcription analysis of 1b-infected hepatoma cells

期刊: ANTIVIRAL RESEARCH, 2021; 193 ()

Globally, hepatitis C virus (HCV) genotype 1b is the most prevalent, and its infection has been found to associate with a higher risk of hepatocellula......

Suppression effect of plant-derived berberine on cyprinid herpesvirus 2 proliferation and its pharmacokinetics in Crucian carp (Carassius auratus gibelio)

期刊: ANTIVIRAL RESEARCH, 2021; 186 ()

Cyprinid herpesvirus 2 (CyHV-2), which infects silver crucian carp including goldfish (Carassius auratus auratus) and Crucian carp (Carassius auratus ......

Investigation of multidrug-resistance mutations of hepatitis B virus (HBV) in a large cohort of chronic HBV-infected patients with treatment of nucleoside/nucleotide analogs

期刊: ANTIVIRAL RESEARCH, 2021; 189 ()

Multidrug-resistance hepatitis B virus (MDR HBV), defined as those with mutations resistant to both nucleoside analogs lamivudine/telbivudine/entecavi......

GS-441524 inhibits African swine fever virus infection in vitro

期刊: ANTIVIRAL RESEARCH, 2021; 191 ()

African swine fever virus (ASFV) is a highly infectious and lethal swine pathogen that causes serious socio-economic consequences in endemic countries......

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