期刊： NEUROBIOLOGY OF AGING, 2022; 113 ()
Spinocerebellar ataxia type 3 (SCA3), also known as Machado Joseph disease (MJD), is a common dom-inantly inherited ataxia, and has heterogeneous clin......
期刊： NEUROBIOLOGY OF AGING, 2022; 120 ()
The related genetic variants of tau deposition, a seminal pathological hallmark of Alzheimer's disease, remain poorly understood. We sought to perform......
期刊： NEUROBIOLOGY OF AGING, 2022; 122 ()
Alterations in the temporal evolution of brain states in the process of cognitive impairment aggrava-tion due to subcortical ischemic vascular disease......
期刊： NEUROBIOLOGY OF AGING, 2022; 109 ()
Recent studies have suggested ARSA, a gene responsible for metachromatic leukodystrophy, could be a genetic modifier of Parkinson's disease (PD) patho......
期刊： NEUROBIOLOGY OF AGING, 2022; 120 ()
Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Pathologically, it is characterized by ,B-amyloid plaques and neurofibri......
期刊： NEUROBIOLOGY OF AGING, 2022; 109 ()
In this study, we examined whether C-reactive protein (CRP) play causal roles in Alzheimer's disease (AD) using Mendelian randomization (MR) analysis.......
期刊： NEUROBIOLOGY OF AGING, 2022; 109 ()
Altered ubiquitin signaling and disrupted protein quality control have been implicated in the pathogenesis of PD. The aim of the study was to systemat......
期刊： NEUROBIOLOGY OF AGING, 2022; 115 ()
Presenilin 1 (PSEN1) mutations are a major cause of familial Alzheimer's disease. The pathogenic variant, PSEN1 p.G417S, has been reported to be assoc......
期刊： NEUROBIOLOGY OF AGING, 2022; 112 ()
Recently, homozygous missense variants in ANXA1 were identified to cause parkinsonism by segregation analysis in a consanguineous family. However, no ......
期刊： NEUROBIOLOGY OF AGING, 2022; 117 ()
Neuropsychiatric symptoms, such as anxiety and depression often appear early in patients with Alzheimer's disease (AD), and a comorbid, anxiety-like p......
期刊： NEUROBIOLOGY OF AGING, 2022; 113 ()
Genetic studies have identified Alzheimer's disease (AD)-associated SNPs in TOMM40 and PVRL2 genes, but the underlying mechanisms remain unknown. We e......
期刊： NEUROBIOLOGY OF AGING, 2022; 110 ()
NUS1 has been recently identified as a candidate gene for Parkinson's disease (PD). Few studies have examined the association of NUS1 variants with PD......
期刊： NEUROBIOLOGY OF AGING, 2022; 116 ()
Despite the similar clinical and pathological features between Niemann-Pick type C (NPC) disease and Alzheimer's disease (AD), few studies have invest......
期刊： NEUROBIOLOGY OF AGING, 2022; 119 ()
Recessive mutations in PRKN, PARK7, and PINK1 are established causes of early-onset Parkinson's disease (EOPD). Previous studies have interrogated the......
期刊： NEUROBIOLOGY OF AGING, 2021; 106 ()
DNAJC7 has recently been recognized as a novel amyotrophic lateral sclerosis (ALS) risk gene. To date, few studies have screened DNAJC7 mutations in C......
