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Analysis of 12 GWAS-Linked Loci With Parkinson's Disease in the Chinese Han Population

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

A recent large-scale European-originated genome-wide association study identified 38 novel independent risk signals in 37 loci for Parkinson's disease......

Use of a Smartphone Application to Speed Up Interhospital Transfer of Acute Ischemic Stroke Patients for Thrombectomy

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Background: In most countries, large cerebral artery occlusion is identified as the leading cause of disability. In 2015, five large-scale clinical tr......

Case Report: Mitochondrial Encephalomyopathy Presents as Epilepsy, Ataxia, and Dystonia With a Rare Mutation in MT-TW

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Mitochondrial diseases are a group of common inherited disorders caused by mutations in nuclear DNA or mitochondrial DNA (mtDNA); the clinical phenoty......

Development of a Prognostic Five-Gene Signature for Diffuse Lower-Grade Glioma Patients

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Background: Diffuse lower-grade gliomas (LGGs) are infiltrative and heterogeneous neoplasms. Gene signature including multiple protein-coding genes (P......

A Systematic Review of the Predictive Value of Plasma D-Dimer Levels for Predicting Stroke Outcome

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Background: Stroke is a leading cause of morbidity and mortality. Over the past decade, plasma D-dimer levels have emerged as a biomarker for predicti......

Mirror Visual Feedback Prior to Robot-Assisted Training Facilitates Rehabilitation After Stroke: A Randomized Controlled Study

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Purpose: Robot-assisted training has been widely used in neurorehabilitation, but its effect on facilitating recovery after stroke remains controversi......

A Dissipation Function-Based Method for Calculating the Energy Loss of Intracranial Aneurysms

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

At present, the energy loss (EL) mechanism of intracranial aneurysm (IA) rupture is explored based on the global EL calculated by Bernoulli equation, ......

Secondary White Matter Injury and Therapeutic Targets After Subarachnoid Hemorrhage

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Aneurysmal subarachnoid hemorrhage (SAH) is one of the special stroke subtypes with high mortality and mobility. Although the mortality of SAH has dec......

Diffusion- and Susceptibility Weighted Imaging Mismatch Correlates With Collateral Circulation and Prognosis After Middle Cerebral Artery M1-Segment Occlusion

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Objective: To explore the relation between diffusion-weighted and susceptibility weighted imaging (DWI-SWI) mismatch and collateral circulation or pro......

DNA Methylation Signature of Epileptic Encephalopathy-Related Pathogenic Genes Encoding Ion Channels in Temporal Lobe Epilepsy

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Epilepsy is characterized by highly abnormal synchronous discharge of brain neurons, and ion channels are fundamental in the generation and modulation......

New Prediction Models of Functional Outcome in Acute Intracerebral Hemorrhage: The dICH Score and uICH Score

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Objectives: The original intracerebral hemorrhage (oICH) score is the severity score most commonly used in clinical intracerebral hemorrhage (ICH) res......

A Comparison of Safety and Effectiveness Between Wingspan and Neuroform Stents in Patients With Middle Cerebral Artery Stenosis

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Background: Percutaneous transluminal angioplasty and stenting with the Wingspan stent has proven safe and effective in patients with middle cerebral ......

Characteristics of Objective Sleep and Its Related Risk Factors Among Parkinson's Disease Patients With and Without Restless Legs Syndrome

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Objective: This study aimed to investigate the objective sleep characteristics and their related risk factors among Parkinson's disease (PD) patients ......

The Distributional Characteristics of Multiple Sclerosis Lesions on Quantitative Susceptibility Mapping and Their Correlation With Clinical Severity

期刊: FRONTIERS IN NEUROLOGY, 2021; 12 ()

Background: Multiple sclerosis (MS) patients have a wide spectrum of severity and responses to therapy; the personalization of treatment relies on sen......

Long-Term Risk Factors for Intracranial In-Stent Restenosis From a Multicenter Trial of Stenting for Symptomatic Intracranial Artery Stenosis Registry in China

期刊: FRONTIERS IN NEUROLOGY, 2021; 11 ()

Background: For patients with symptomatic intracranial artery stenosis (sICAS), endovascular treatment has been shown to be feasible and safe in recen......

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