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New insights into segmental vitiligo: A clinical and immunological comparison with nonsegmental vitiligo

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2022; 35 (2)

The overlaps between segmental vitiligo (SV) and nonsegmental vitiligo (NSV) suggest the underlying features of SV, which may be helpful for treating ......

JIF:3.704

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) sensitize melanoma cells to MEK inhibition and inhibit metastasis and relapse by inducing degradation of AXL

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2022; 35 (2)

Melanoma is highly heterogeneous with diverse genomic alterations and partial therapeutic responses. The emergence of drug-resistant tumor cell clones......

JIF:3.704

New insights into the pathogenesis of Hermansky-Pudlak syndrome

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2022; 35 (3)

Hermansky-Pudlak syndrome (HPS) is characterized by defects of multiple tissue-specific lysosome-related organelles (LROs), typically manifesting with......

JIF:3.704

Altered expression of ferroptosis markers and iron metabolism reveals a potential role of ferroptosis in vitiligo

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2022; 35 (3)

Oxidative stress is one of the triggering factors for vitiligo, which leads to melanocyte (MC) destruction in vitiligo lesions. Ferroptosis, which is ......

JIF:3.704

The impaired unfolded protein-premelanosome protein and transient receptor potential channels-autophagy axes in apoptotic melanocytes in vitiligo

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2022; 35 (1)

Vitiligo is an autoimmune skin disease, characterized by depigmentation and epidermal melanocytes loss. The specific mechanisms underlying vitiligo ha......

JIF:3.704

Establishment and characterization of an immortalized human giant congenital melanocytic nevi cell line

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2022; 35 (3)

Treatments for giant congenital melanocytic nevi (GCMN) are extremely limited. Thus, there is an urgent need for development of relevant targeted ther......

JIF:3.704

The fate of melanocyte: Mechanisms of cell death in vitiligo

期刊: PIGMENT CELL & MELANOMA RESEARCH, ; ()

Loss of melanocytes (MCs) is the most notable feature of vitiligo. Hence, it is critical to clarify the mechanisms of MC destruction in vitiligo. Apop......

The fate of melanocyte: Mechanisms of cell death in vitiligo

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2021; 34 (2)

Loss of melanocytes (MCs) is the most notable feature of vitiligo. Hence, it is critical to clarify the mechanisms of MC destruction in vitiligo. Apop......

Distinct genomic traits of acral and mucosal melanomas revealed by targeted mutational profiling

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2020; 33 (4)

The incidence of melanoma is rising globally including China. Comparing to Caucasians, the incidence of non-cutaneous melanomas is significantly highe......

CD147 regulates melanoma metastasis via the NFAT1-MMP-9 pathway

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2020; 33 (5)

Although accumulating evidence had revealed that NFAT1 has oncogenic characteristics, the role of this molecule in melanoma cells remains unclear. Pre......

A ROCK inhibitor promotes keratinocyte survival and paracrine secretion, enhancing establishment of primary human melanocytes and melanocyte-keratinocyte co-cultures

期刊: PIGMENT CELL & MELANOMA RESEARCH, 0; ()

Primary melanocytes isolated from skin and expanded in culture have been widely used for laboratory research and clinical applications. The convention......

Instability of BLOC-2 and BLOC-3 in Chinese patients with Hermansky-Pudlak syndrome

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2019; 32 (3)

Hermansky-Pudlak syndrome (HPS) is a rare recessive disorder characterized by oculocutaneous albinism (OCA) or ocular albinism (OA), bleeding tendency......

JIF:4.17

Comprehensive analysis of spectral distribution of a large cohort of Chinese patients with non-syndromic oculocutaneous albinism facilitates genetic diagnosis

期刊: PIGMENT CELL & MELANOMA RESEARCH, 2019; 32 (5)

Non-syndromic oculocutaneous albinism (nsOCA) is a group of genetically heterogeneous autosomal recessive disorders with complete lack or decrease pig......

JIF:4.17

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