期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (1)
Inflammatory bowel disease (IBD) is a global health burden whose existing treatment is largely dependent on anti-inflammatory agents. Despite showing ......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (1)
Inflammation is one of the pathogenic processes in Parkinson's disease (PD). Dopamine receptor agonist pramipexole (PPX) is extensively used for PD tr......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (2)
Abdominal aortic aneurysm (AAA) is a dangerous vascular disease without any effective drug therapies so far. Emerging evidence suggests the phenotypic......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (4)
Herpes simplex virus (HSV) infection induces a rapid and transient increase in intracellular calcium concentration ([Ca2+](i)), which plays a critical......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; ()
Obesity contributes to the progression of various chronic diseases, and shortens life expectancy. With abundant mitochondria, brown adipose tissue (BA......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; ()
Meteorin-like (Metrnl) is a novel secreted protein with various biological activities. In this study, we investigated whether and how Metrnl regulated......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; ()
Diabetic nephropathy (DN) is characterized by chronic low-grade renal inflammatory responses, which greatly contribute to disease progression. Abnorma......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; ()
Stimulation of adult cardiomyocyte proliferation is a promising strategy for treating myocardial infarction (MI). Earlier studies have shown increased......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (2)
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease. Cyst development in ADPKD involves abnormal epitheli......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (3)
Long-term treatment with adriamycin (ADR) is associated with higher incidences of cumulative cardiotoxicity manifest as heart failure. ADR-induced car......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (4)
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is still raging. However, the pathophysiology of acute and post-a......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (4)
Liposomes decorated with tumour-targeting cell-penetrating peptides can enhance specific drug delivery at the tumour site. The TR peptide, c(RGDfK)-AG......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (4)
Anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the treatment of neovascular eye diseases, but responses are incomplete in so......
期刊: ACTA PHARMACOLOGICA SINICA, 2023; 44 (5)
Ferroptosis is a new form of regulated cell death characterized by excessive iron accumulation and uncontrollable lipid peroxidation. The role of ferr......