筛选条件 共查询到180条结果
排序方式
Efficacy and safety of CD19-specific CAR T cell-based therapy in B-cell acute lymphoblastic leukemia patients

期刊: BLOOD, 2022; 139 (23)

Few studies have described chimeric antigen receptor (CAR) T-cell therapy for patients with B-cell acute lymphoblastic leukemia (B-ALL) with central n......

JIF:7.405

Protein tyrosine phosphatase PTPN22 negatively modulates platelet function and thrombus formation

期刊: BLOOD, 2022; 140 (9)

Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) is a protein tyrosine phosphatase that negatively regulates T-cell signaling. However, wheth......

JIF:7.405

Structural basis of von Willebrand factor multimerization and tubular storage

期刊: BLOOD, 2022; 139 (22)

The von Willebrand factor (VWF) propeptide (domains D1D2) is essential for the assembly of VWF multimers and its tubular storage in Weibel-Palade bodi......

JIF:7.405

RAR gamma activation sensitizes human myeloma cells to carfilzomib treatment through the OAS-RNase L innate immune pathway

期刊: BLOOD, 2022; 139 (1)

Proteasome inhibitors (Pis) such as bortezomib (Btz) and carfilzomib (Cfz) are highly efficacious for patients with multiple myeloma (MM). However, re......

JIF:7.405

A study of ruxolitinib response-based stratified treatment for pediatric hemophagocytic lymphohistiocytosis

期刊: BLOOD, 2022; 139 (24)

Hemophagocytic lymphohistiocytosis (HLH) is a lethal disorder characterized by hyperinflammation. Recently, ruxolitinib (RUX), targeting key cytokines......

JIF:7.405

Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches

期刊: BLOOD, 2022; 139 (10)

Bone marrow niche cells have been reported to fine-tune hematopoietic stem cell (HSC) stemness via direct interaction or secreted components. Neverthe......

JIF:7.405

Low-dose decitabine modulates myeloid-derived suppressor cell fitness via LKB1 in immune thrombocytopenia

期刊: BLOOD, 2022; 140 (26)

Myeloid-derived suppressor cells (MDSCs) are heterogeneous immature cells and natural inhibitors of adaptive immunity. Metabolic fitness of MDSCs is f......

JIF:7.405

Grab regulates transferrin receptor recycling and iron uptake in developing erythroblasts

期刊: BLOOD, 2022; 140 (10)

Developing erythroblasts acquire massive amounts of iron through the transferrin (Tf) cycle, which involves endocytosis, sorting, and recycling of the......

JIF:7.405

Zanubrutinib in relapsed/refractory mantle cell lymphoma: long-term efficacy and safety results from a phase 2 study

期刊: BLOOD, 2022; 139 (21)

Bruton tyrosine kinase (BTK) inhibitor is an established treatment for relapsed/refractory (R/R) mantle cell lymphoma (MCL). Zanubrutinib, a highly se......

JIF:7.405

The RIG-I-NRF2 axis regulates the mesenchymal stromal niche for bone marrow transplantation

期刊: BLOOD, 2022; 139 (21)

Bone marrow-derived mesenchymal stem cells (BMSCs) support bone formation and constitute the stromal niche in regulating hematopoietic stem cells (HSC......

JIF:7.405

PEG10 amplification at 7q21.3 potentiates large-cell transformation in cutaneous T-cell lymphoma

期刊: BLOOD, 2022; 139 (4)

Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma, undergo large-cell transformation (LCT) in the late stage, manifesting aggr......

JIF:7.405

Deciphering the continuum of hemogenic endothelium differentiation

期刊: BLOOD, 2022; 139 (3)

In this issue of Blood, Fadlullah et al(1) construct a comprehensive atlas of the endothelial-to-hematopoietic transition (EHT) continuum, as well as ......

JIF:7.405

共180条页码: 1/12页15条/页