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The Response Measures to the Coronavirus Disease 2019 Outbreak in China

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (2)

For China, the coronavirus disease 2019 (COVID-19) outbreak is a major public health emergency with the fastest spread, the most extensive infection, ......

Manganese Breaks the Immune Tolerance of HBs-Ag

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (2)

Background. Manganese (Mn2+) has been shown to promote type I interferon (IFN) production and activate the cyclic GMP-AMP synthase (cGAS)/Stimulator o......

Cytokine and Chemokine Levels in Coronavirus Disease 2019 Convalescent Plasma

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (2)

Background. The efficacy of coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) is primarily ascribed as a source of neutralizing anti-sever......

Analysis of the Driving Factors of Active and Rapid Growth Clusters Among CRF07_BC-Infected Patients in a Developed Area in Eastern China

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (3)

Background. The purpose of this study was to research the molecular transmission and genetic evolutionary characteristics among CRF07_BC-infected pati......

Do Stay at Home Orders and Cloth Face Coverings Control COVID-19 in New York City? Results From a SIER Model Based on Real-world Data

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (2)

Background. Public health interventions have been implemented to contain the outbreak of coronavirus disease 2019 (COVID-19) in New York City. However......

While We Endure This Pandemic, What New Respiratory Virus Threats Are We Missing?

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (3)

In this paper, we review recent human respiratory virus epidemics, their zoonotic nature, and our current inability to identify future prepandemic thr......

Clinical Effectiveness of Intravenous Peramivir Compared With Oseltamivir in Patients With Severe Influenza A With Primary Viral Pneumonia: A Randomized Controlled Study

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (1)

Background. High-quality evidence confirms that the clinical efficacy of peramivir in severe influenza patients with primary viral pneumonia is lackin......

Novel Beta-Lactam/Beta-Lactamase Plus Metronidazole vs Carbapenem for Complicated Intra-abdominal Infections: A Meta-analysis of Randomized Controlled Trials

期刊: OPEN FORUM INFECTIOUS DISEASES, 2021; 8 (1)

Background. Complicated intra-abdominal infections (cIAIs) remain a leading cause of death in surgical wards, in which antibiotic treatment is crucial......

Human Case Infected With Babesia venatorum: A 5-Year Follow-Up Study

期刊: OPEN FORUM INFECTIOUS DISEASES, 2020; 7 (3)

Background. Human babesiosis is a common zoonosis caused by Babesia and is attracting an increasing concern worldwide. The natural course of babesiosi......

High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019

期刊: OPEN FORUM INFECTIOUS DISEASES, 2020; 7 (3)

The outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly in China. Until now, no definite effective treatment has been identified. We re......

Poor Outcomes of Acute Hepatitis E in Patients With Cirrhotic Liver Diseases Regardless of Etiology

期刊: OPEN FORUM INFECTIOUS DISEASES, 2020; 7 (4)

Background: Chronic liver diseases (CLDs) have been documented to exacerbate clinical outcomes of acute hepatitis E (AHE). This study aimed to uncover......

The Central Role of Nondisclosed Men Who Have Sex With Men in Human Immunodeficiency Virus-1 Transmission Networks in Guangzhou, China

期刊: OPEN FORUM INFECTIOUS DISEASES, 2020; 7 (5)

Background. Men who have sex with men (MSM) are vulnerable risk group for human immunodeficiency virus (HIV)-1 infection. However, some MSM do not dis......

Differentiating Between 2019 Novel Coronavirus Pneumonia and Influenza Using a Nonspecific Laboratory Marker-Based Dynamic Nomogram

期刊: OPEN FORUM INFECTIOUS DISEASES, 2020; 7 (5)

Background. There is currently a lack of nonspecific laboratory indicators as a quantitative standard to distinguish between the 2019 coronavirus dise......

C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation

期刊: OPEN FORUM INFECTIOUS DISEASES, 2020; 7 (5)

Background. Clinical findings indicated that a fraction of coronavirus disease 2019 (COVID-19) patients diagnosed as mild early may progress to severe......

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