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MMP1 regulated by NEAT1/miR-361-5p axis facilitates the proliferation and migration of cutaneous squamous cell carcinoma via the activation of Wnt pathway

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (5-6)

Cutaneous squamous cell carcinoma (CSCC) is one of the most malignant tumors worldwide. It has been validated that matrix metallopeptidase 1 (MMP1) ex......

Long non-coding RNA TDRG1 facilitates cell proliferation, migration and invasion in breast cancer via targeting miR-214-5p/CLIC4 axis

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (3)

Accumulated studies have revealed the critical role of long non-coding RNAs (lncRNAs) in the carcinogenesis and progression of various cancers. LncRNA......

Tripartite motif protein 11 (TRIM11), an oncogene for human lung cancer via the DUSP6-mediated ERK1/2 signaling pathway

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (4)

Evidence suggests that Tripartite Motif Containing 11 (TRIM11) has pro-tumor activity in human non-small cell lung cancer (NSCLC). However, the roles ......

The role of CD133 in hepatocellular carcinoma

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (4)

Cancer stem cells (CSCs) represent a small subpopulation of cells found within tumors that exhibit properties of self-renewal, like normal stem cells.......

The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ)

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (5-6)

A maximal surgical resection followed by radiotherapy and chemotherapy with temozolomide (TMZ) as the representative agent is the standard therapy for......

LINC00668 cooperated with HuR dependent upregulation of PKN2 to facilitate gastric cancer metastasis

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (4)

In China, gastric cancer (GC) ranks first in the incidence of all malignant tumors. With high recurrence and distant metastasis, GC has caused conside......

NCK1-AS1 promotes the progression of lung squamous cell carcinoma through transcriptionally upregulating NCK1 via interacting with MYC

期刊: CANCER BIOLOGY & THERAPY, ; ()

Lung squamous cell carcinoma (LUSC) is a prevalent subtype of nonsmall cell lung cancer (NSCLC). Dysregulated long noncoding RNAs (lncRNAs) are increa......

Zfx-induced upregulation of UBE2J1 facilitates endometrial cancer progression via PI3K/AKT pathway

期刊: CANCER BIOLOGY & THERAPY, ; ()

Emerging documents revealed that E2 enzyme family has been implicated in regulating the progression of numerous human cancers. Ubiquitin-conjugating e......

YY1-inudced activation of lncRNA DUXAP8 promotes proliferation and suppresses apoptosis of triple negative breast cancer cells through upregulating SAPCD2

期刊: CANCER BIOLOGY & THERAPY, ; ()

Double homeobox A pseudogene 8 (DUXAP8) belongs to long non-coding RNAs (lncRNAs), which has been proven to promote the biological processes of multip......

Integration of radiotherapy with anti-PD-1 antibody for the treatment of intrahepatic or hilar cholangiocarcinoma: reflection from four cases

期刊: CANCER BIOLOGY & THERAPY, ; ()

Cholangiocarcinoma (CCA) represents a clinically challenging disease with a dismal prognosis. A therapeutic plateau has been reached with traditional ......

LncRNA FGD5-AS1 accelerates cell proliferation in pancreatic cancer by regulating miR-520a-3p/KIAA1522 axis

期刊: CANCER BIOLOGY & THERAPY, ; ()

In recent years, FGD5 antisense RNA 1 (FGD5-AS1) was confirmed to be the long non-coding RNAs (lncRNAs) that could accelerate the development of multi......

Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model

期刊: CANCER BIOLOGY & THERAPY, ; ()

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers in the modern world, in part due to poor delivery of chemotherapeutics. Sonopo......

Evaluation of microRNAs as potential biomarkers in circulating HPV-DNA-positive non-small cell lung cancer patients

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (2)

The aim of the present study was to identify the potential risk of circulating-HPV-DNA in non-small cell lung cancer (NSCLC) and to analyze abnormally......

Difficult differential diagnosis of bladder pedicled masses about metastasis from non-small cell lung cancer: A case report

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (2)

Differential diagnoses of primary bladder tumors from metastasis ones can be difficult, for the symptom and imaging findings are pretty similar. Here,......

NF-kappa B pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis

期刊: CANCER BIOLOGY & THERAPY, 2021; 22 (2)

Stearoyl-CoA-desaturase 1 (SCD1) deficiency mediates apoptosis in colorectal cancer cells by promoting ceramide de novo synthesis. The mechanisms unde......

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