期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (6)
Profiling heterologous cell types within tumors is essential to decipher tumor microenvironment that shapes tumor progress and determines the outcome ......
期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (6)
Background Pancreatic adenocarcinoma (PAAD) a highly lethal malignancy. The current use of clinical parameters may not accurately predict the clinical......
期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (3)
Background Treatment of hemophiliacs with inhibitors remains challenging, and new treatments are in urgent need. Coagulation factor X plays a critical......
期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (5)
Background and purpose Osteoporosis is characterized by excessive bone resorption due to enhanced osteoclast activation. Stimulation of nuclear factor......
期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (6)
Although the treatment of osteosarcoma has improved, the overall survival rate of this common type of osseous malignancies has not changed for four de......
期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (6)
Exosomes are small extracellular vesicles 40-160 nm in diameter that are secreted by almost all cell types. Exosomes can carry diverse cargo including......
期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (6)
Tau accumulation and cholinergic impairment are characteristic pathologies in Alzheimer's disease (AD). However, the causal role of tau accumulation i......
期刊: CLINICAL AND TRANSLATIONAL MEDICINE, 2021; 11 (7)
Background In vitro fertilization (IVF) with preimplantation genetic testing (PGT) has markedly improved clinical pregnancy outcomes for carriers of g......