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MiR-128-1-5p inhibits cell proliferation and induces cell apoptosis via targeting PRKCQ in colorectal cancer

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Previous studies have indicated that miR-128 was downregulated in a variety of cancers including colorectal cancer (CRC). However, the role and the un......

A study on metabolic characteristics and metabolic markers of gastrointestinal tumors

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Tumor cells have significant heterogeneity in metabolism and are closely related to prognosis, gene mutation, and subtype. However, this association h......

Netrin-1 inducing antiapoptotic effect of acute myeloid leukemia cells in a concentration-dependent manner through the Unc-5 netrin receptor B-focal adhesion kinase axis

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Acute myeloid leukemia (AML) is a hematological malignancy that commonly occurs in children. The prognosis of pediatric AML is relatively poor, thus t......

Transcription factor 3 promotes migration and invasion potential and maintains cancer stemness by activating ID1 expression in esophageal squamous cell carcinoma

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Transcription factor 3 (TCF3) is a member of the basic Helix - Loop - Helix (bHLH) transcription factor (TF) family and is encoded by the TCF3 gene (a......

Identification of USP29 as a key regulator of nucleotide biosynthesis in neuroblastoma through integrative analysis of multi-omics data

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Cancer cells show enhanced nucleotide biosynthesis, which is essential for their unlimited proliferation, but the underlying mechanisms are not entire......

The impact of radiation dose on the efficacy of definitive chemoradiotherapy in patients with locally advanced esophageal carcinoma: a systematic review and meta-analysis

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

To investigate the impact of radiation dose on the efficacy of definitive chemoradiotherapy(dCCRT) in patients with locally advanced esophageal carcin......

MiR-597-5p inhibits carcinogenesis and macrophage recruitment in colitis-related colorectal cancer via reducing the expression of CXCL5

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Despite being the subject of multiple cancer studies, nothing is known about miR-597-5p's role in colitis-associated colorectal cancer (CAC). We inten......

CircSETD2 inhibits YAP1 by interaction with HuR during breast cancer progression

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

CircRNAs have been proven to play a pivotal role in cancer progression. The present study aims to explore the roles and related mechanisms of circSETD......

PLK4 inhibitor exhibits antitumor effect and synergizes sorafenib via arresting cell cycle and inactivating Wnt/β-catenin pathway in anaplastic thyroid cancer

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

The anti-tumor effect of polo-like kinase 4 (PLK4) inhibitor has been explored in several solid carcinomas, while its application in anaplastic thyroi......

Drug repurposing based on differentially expressed genes suggests drug combinations with possible synergistic effects in treatment of lung adenocarcinoma

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Lung adenocarcinoma is one of the leading causes of cancer-related mortality globally. Various treatment approaches and drugs had little influence on ......

The impact of drug-eluting bead (vs. conventional) transarterial chemoembolization on hepatic fibrosis in treating intermediate or advanced hepatocellular carcinoma

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Objective Limited studies have reported the impact of drug-eluting bead transarterial chemoembolization (DEB-TACE) on hepatic fibrosis in hepatocellul......

Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Sinapine thiocyanate (ST), an alkaloid existed extensively in seeds of cruciferous plants, exhibits a number of pharmacological effects, including ant......

Ras interacting protein 1 facilitated proliferation and invasion of diffuse large B-cell lymphoma cells

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

A GTPase binding protein, Ras interacting protein 1 (RASIP1), has been reported with a tumor-promoting role in lung cancer cells, and its role in lymp......

EGR1/LINC00839/SOX5 axis modulates migration, invasion and Gemcitabine resistance of bladder cancer cells

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Background: Bladder cancer is one of the most common malignant tumors of the urinary system, and its incidence is increasing worldwide. However, the u......

CSTF2T facilitates pancreatic adenocarcinoma growth and metastasis by elevating H3K4Me1 methylation of CALB2 via ASH2L

期刊: CANCER BIOLOGY & THERAPY, 2023; 24 (1)

Pancreatic adenocarcinoma (PAAD) is a major cause of mortality related to cancer worldwide. This paper dissected the functions of the CSTF2T/ASH2L/CAL......

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