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Lipidomics-Paving the Road towards Better Insight and Precision Medicine in Rare Metabolic Diseases

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (2)

Even though the application of Next-Generation Sequencing (NGS) has significantly facilitated the identification of disease-associated mutations, the ......

Unexpected Crosslinking Effects of a Human Thyroid Stimulating Monoclonal Autoantibody, M22, with IGF1 on Adipogenesis in 3T3L-1 Cells

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (2)

To study the effects of the crosslinking of IGF1 and/or the human thyroid-stimulating monoclonal autoantibody (TSmAb), M22 on mouse adipocytes, two- a......

The Association between the Bisphenols Residues in Amniotic Fluid and Fetal Abnormalities in Polish Pregnant Women-Its Potential Clinical Application

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

The present study aimed to investigate the relationship between the concentrations of bisphenols residues in the amniotic fluid (AF) samples collected......

Optical Fiber Grating-Prism Fabrication by Imprint Patterning of Ionic-Liquid-Based Resist

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (2)

We present a method of microstructure fabrication on the tip of the optical fiber using a UV soft-imprint process of polymerizable ionic liquid-based ......

Neural Network in the Analysis of the MR Signal as an Image Segmentation Tool for the Determination of T1 and T2 Relaxation Times with Application to Cancer Cell Culture

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (2)

Artificial intelligence has been entering medical research. Today, manufacturers of diagnostic instruments are including algorithms based on neural ne......

The SDHD:p.H102R Variant Is Frequent in Russian Patients with Head and Neck Paragangliomas and Associated with Loss of 11p15.5 Region and Hypermethylation of H19-DMR

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Head and neck paragangliomas (HNPGLs) are rare neuroendocrine neoplasms derived from the parasympathetic paraganglia of the head and neck. At least 30......

Nrf2 Activation: Involvement in Central Nervous System Traumatic Injuries. A Promising Therapeutic Target of Natural Compounds

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Central nervous system (CNS) trauma, such as traumatic brain injury (TBI) and spinal cord injury (SCI), represents an increasingly important health bu......

Tricarboxylic Acid Metabolite Imbalance in Rats with Acute Thioacetamide-Induced Hepatic Encephalopathy Indicates Incomplete Recovery

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (2)

Exposure to the toxin thioacetamide (TAA) causes acute hepatic encephalopathy (HE), changes in the functioning of systemic organs, and an imbalance in......

The Normobaric Oxygen Paradox-Hyperoxic Hypoxic Paradox: A Novel Expedient Strategy in Hematopoiesis Clinical Issues

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Hypoxia, even at non-lethal levels, is one of the most stressful events for all aerobic organisms as it significantly affects a wide spectrum of physi......

The Role of B Cell and T Cell Glycosylation in Systemic Lupus Erythematosus

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Glycosylation is a post-translational modification that affects the stability, structure, antigenicity and charge of proteins. In the immune system, g......

Dextran Sulfate Nanocarriers: Design, Strategies and Biomedical Applications

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Dextran sulfate (DXS) is a hydrophilic, non-toxic, biodegradable, biocompatible and safe biopolymer. These biomedically relevant characteristics make ......

Effects of Oleuropein and Hydroxytyrosol on Inflammatory Mediators: Consequences on Inflammaging

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Aging is associated with a low-grade, systemic inflammatory state defined as inflammaging, ruled by the loss of proper regulation of the immune system......

Hippocampal Deletion of CB1 Receptor Impairs Social Memory and Leads to Age-Related Changes in the Hippocampus of Adult Mice

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Endocannabinoid system activity declines with age in the hippocampus, along with the density of the cannabinoid receptor type-1 (CB1). This process mi......

Adjustment of the Structure of the Simplest Amino Acid Present in Nature-Glycine, toward More Environmentally Friendly Ionic Forms of Phenoxypropionate-Based Herbicides

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (2)

The use of chemicals for various purposes in agriculture has numerous consequences, such as the contamination of ecosystems. Thus, nowadays it is perc......

Aptamers for Addressed Boron Delivery in BNCT: Effect of Boron Cluster Attachment Site on Functional Activity

期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023; 24 (1)

Among the great variety of anti-cancer therapeutic strategies, boron neutron capture therapy (BNCT) represents a unique approach that doubles the targ......

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