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Temporal trajectories of important diseases in the life course and premature mortality in the UK Biobank

期刊: BMC MEDICINE, 2022; 20 (1)

Background Little is known regarding life-course trajectories of important diseases. We aimed to identify diseases that were strongly associated with ......

JIF:7.859

Deep learning radiomics of dual-modality ultrasound images for hierarchical diagnosis of unexplained cervical lymphadenopathy

期刊: BMC MEDICINE, 2022; 20 (1)

Background Accurate diagnosis of unexplained cervical lymphadenopathy (CLA) using medical images heavily relies on the experience of radiologists, whi......

JIF:7.859

Effectiveness of early rhythm control in improving clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis

期刊: BMC MEDICINE, 2022; 20 (1)

Background Current guidelines recommend rhythm control for improving symptoms and quality of life in symptomatic patients with atrial fibrillation (AF......

JIF:7.859

Influence of baseline arterial stiffness on effects of intensive compared with standard blood pressure control: a post hoc analysis of the STEP trial

期刊: BMC MEDICINE, 2022; 20 (1)

Background: The benefits and risks of intensive versus standard systolic blood pressure (SBP) treatment in older patients with arterial stiffness (AS)......

JIF:7.859

SIRP alpha antibody combined with oncolytic virus OH2 protects against tumours by activating innate immunity and reprogramming the tumour immune microenvironment

期刊: BMC MEDICINE, 2022; 20 (1)

Background: The combination of oncolytic viruses (OVs) with immune checkpoint blockades is a research hotspot and has shown good efficacy. Here, we pr......

JIF:7.859

Frequency of adding salt at the table and risk of incident cardiovascular disease and all-cause mortality: a prospective cohort study

期刊: BMC MEDICINE, 2022; 20 (1)

Background: Adding salt at the table is a prevalent eating habit, but its long-term relationship with cardiovascular disease (CVD) and all-cause morta......

JIF:7.859

Identification of heart failure with preserved ejection fraction helps risk stratification for hypertrophic cardiomyopathy

期刊: BMC MEDICINE, 2022; 20 (1)

Background Heart failure with preserved ejection fraction (HFpEF) is the dominant form of heart failure (HF). We here aimed to investigate the charact......

JIF:7.859

Prediction of long-term kinetics of vaccine-elicited neutralizing antibody and time-varying vaccine-specific efficacy against the SARS-CoV-2 Delta variant by clinical endpoint

期刊: BMC MEDICINE, 2022; 20 (1)

Background Evidence on vaccine-specific protection over time, in particular against the Delta variant, and protection afforded by a homologous third d......

JIF:7.859

The association between assisted reproductive technology and cardiac remodeling in fetuses and early infants: a prospective cohort study

期刊: BMC MEDICINE, 2022; 20 (1)

Background: Limited data exist regarding the potential impact of assisted reproductive technology (ART) on cardiac remodeling. In particular, whether ......

JIF:7.859

Temporal relationship among adiposity, gut microbiota, and insulin resistance in a longitudinal human cohort

期刊: BMC MEDICINE, 2022; 20 (1)

Background: The temporal relationship between adiposity and gut microbiota was unexplored. Whether some gut microbes lie in the pathways from adiposit......

JIF:7.859

Number of standard modifiable risk factors and mortality in patients with first-presentation ST-segment elevation myocardial infarction: insights from China Acute Myocardial Infarction registry

期刊: BMC MEDICINE, 2022; 20 (1)

Background Recent publications reported a paradoxical finding that there was an inverse association between the number of standard modifiable risk fac......

JIF:7.859

Associations of face-to-face and non-face-to-face social isolation with all-cause and cause-specific mortality: 13-year follow-up of the Guangzhou Biobank Cohort study

期刊: BMC MEDICINE, 2022; 20 (1)

Background Although social isolation has been associated with a higher mortality risk, little is known about the potential different impacts of face-t......

JIF:7.859

The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study

期刊: BMC MEDICINE, 2022; 20 (1)

Background Circulating levels of amino acids were associated with blood pressure (BP) in observational studies. However, the causation of such associa......

JIF:7.859

Prophylactic antibiotic use during labor and delivery in China: a nationwide, multicenter, hospital-based, cross-sectional study

期刊: BMC MEDICINE, 2022; 20 (1)

Background Prophylactic antibiotic use during delivery is common in routine obstetric practice to prevent infection globally, especially in low- and m......

JIF:7.859

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