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Ca2+-activated chloride channel ANO1: A new regulator of osteoclast function Comment

期刊: CELL CALCIUM, 2022; 106 ()

A paper by Sun et al. identified the Ca2+-activated Cl- channel anoctamin 1 or ANO1 (TMEM16A) as an important regulator of osteoclast function by inte......

JIF:5.802

Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7

期刊: CELL CALCIUM, 2022; 106 ()

The transient receptor potential cation channel, subfamily M, members 6 and 7 (TRPM6 and TRPM7) are homologous membrane proteins encompassing cation c......

JIF:5.802

Altered composition of the mitochondrial Ca(2+)uniporter in the failing human heart

期刊: CELL CALCIUM, 2022; 105 ()

Heart failure (HF) is a leading cause of hospitalization and mortality worldwide. Yet, there is still limited knowledge on the underlying molecular me......

JIF:5.802

TRPC1 channels regulate the activation of pancreatic stellate cells through ERK1/2 and SMAD2 pathways and perpetuate their pressure-mediated activation

期刊: CELL CALCIUM, 2022; 106 ()

Pancreatic stellate cell (PSC) activation is a major event occurring during pancreatic ductal adenocarcinoma (PDAC) development. Up to now mechanisms ......

JIF:5.802

Channelopathy-causing mutations in the S(45)A/S45B and HA/HB helices of K(Ca)2.3 and K(Ca)3.1 channels alter their apparent Ca2+ sensitivity

期刊: CELL CALCIUM, 2022; 102 ()

Small-and intermediate-conductance Ca2+-activated potassium (KCa2.x and KCa3.1, also called SK and IK) channels are activated exclusively by a Ca-2+-c......

JIF:5.802

Modulation of carbachol-induced Ca2+ oscillations in airway smooth muscle cells by PGE(2)

期刊: CELL CALCIUM, 2022; 103 ()

PGE(2) is a potent bronchodilator, but the mechanisms underlying this effect have not been fully elucidated. Acetylcholine-induced contractions of air......

JIF:5.802

CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer

期刊: CELL CALCIUM, 2022; 103 ()

Androgen deprivation therapy (ADT) is the main treatment for advanced prostate cancer (PCa) but resistance results in progression to terminal castrate......

JIF:5.802

The evolution of organellar calcium mapping technologies

期刊: CELL CALCIUM, 2022; 108 ()

Intracellular Ca2+ fluxes are dynamically controlled by the co-involvement of multiple organellar pools of stored Ca2+. Endolysosomes are emerging as ......

JIF:5.802

Presynaptic-like mechanisms and the control of insulin secretion in pancreatic beta-cells.

期刊: CELL CALCIUM, 2022; 104 ()

Exocytotic release of hormones from endocrine cells must encompass mechanisms that direct the hormone into the blood stream. Increasing evidence indic......

JIF:5.802

Neurophysiological functions and pharmacological tools of acidic and non-acidic Ca2+ stores

期刊: CELL CALCIUM, 2022; 104 ()

Ca2+ signalling is of prime importance in controlling numerous cell functions in the brain. Endolysosomes are acidic organelles currently emerging as ......

JIF:5.802

Full-fusion and kiss-and-run in chromaffin cells controlled by irreversible vesicle size-dependent fusion pore transitions

期刊: CELL CALCIUM, 2022; 105 ()

Exocytosis operates through two distinct modes. Full-fusion leads to rapid expulsion of the entire content of a vesicle; kiss-and-run leads to slow an......

JIF:5.802

IN BRAIN POST-ISCHEMIC PLASTICITY, Na+/Ca2+ EXCHANGER 1 AND Ascl1 INTERVENE IN MICROGLIA-DEPENDENT CONVERSION OF ASTROCYTES INTO NEURONAL LINEAGE

期刊: CELL CALCIUM, 2022; 105 ()

The intricate glia interaction occurring after stroke strongly depend on the maintenance of intraglial ionic homeostasis. Among the several ionic chan......

JIF:5.802

Na+/Ca2+ exchanger isoform 1 (NCX1) and canonical transient receptor potential channel 6 (TRPC6) are recruited by STIM1 to mediate Store-Operated Calcium Entry in primary cortical neurons

期刊: CELL CALCIUM, 2022; 101 ()

Excessive calcium (Ca2+) release from the endoplasmic reticulum (ER) represents an important hallmark of several neurodegenerative diseases. ER is rec......

JIF:5.802

Oncomodulin (OCM) uniquely regulates calcium signaling in neonatal cochlear outer hair cells

期刊: CELL CALCIUM, 2022; 105 ()

In cochlear outer hair cells (OHCs), a network of Ca2+ channels, pumps and Ca2+-binding proteins (CaBPs) regulates the localization, spread, and magni......

JIF:5.802

Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7

期刊: CELL CALCIUM, 2022; 106 ()

The bifunctional cation channel/kinase TrpM7 is ubiquitously expressed and regulates embryonic development and pathogenesis of several common diseases......

JIF:5.802

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