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Chemotherapy in idiopathic pulmonary fibrosis and small-cell lung cancer with poor lung function

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease with unclear pathogenesis. IPF is considered as a risk factor fo......

Downregulation of the PD-1/PD-Ls pathway in peripheral cells correlates with asbestosis severity

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Asbestosis and silicosis are characterized by diffuse or nodular interstitial lung fibrosis resulting from exposure to asbestos or silica d......

Massive haemorrhagic complications of ruptured pulmonary arteriovenous malformations: outcomes from a 12 years' retrospective study

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

BackgroundThe life-threatening haemorrhagic complications of pulmonary arteriovenous malformations (PAVMs) are extremely rare, and only described in i......

Household mold exposure interacts with inflammation-related genetic variants on childhood asthma: a case-control study

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background A number of studies have examined the association between mold exposure and childhood asthma. However, the conclusions were inconsistent, w......

Innovative method for Amplatzer device implantation in patients with bronchopleural fistulas

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Bronchopleural fistula (BPF) is a relatively rare complication after various types of pulmonary resection. The double-sided mushroom-shaped......

An uncommon etiological factor for aspiration pneumonitis caused by spontaneous sphenoid sinus meningoencephalocele with cerebrospinal fluid rhinorrhea: a case report

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Aspiration pneumonitis is an inflammatory disease of the lungs which is difficult to diagnose accurately. Large-volume aspiration of oropha......

A predictive tool for the assessment of right ventricular dysfunction in non-high-risk patients with acute pulmonary embolism

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

BackgroundRapid and accurate identification of right ventricular (RV) dysfunction is essential for decreasing mortality associated with acute pulmonar......

Osimertinib versus afatinib in patients with T790M-positive, non-small-cell lung cancer and multiple central nervous system metastases after failure of initial EGFR-TKI treatment

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background: The purpose of this study was to compare the efficacy of osimertinib (OSI) versus afatinib (AFA) in patients with T790M-positive, non-smal......

Anti-TIF1 gamma-positive IPAF patient developed stage IVB lung squamous carcinoma in 1 year: a case report

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

BackgroundPatients with connective tissue disease, such as dermatomyositis (DM), and positive anti-TIF1 gamma self-antibodies are commonly diagnosed w......

LINC01089 suppresses lung adenocarcinoma cell proliferation and migration via miR-301b-3p/STARD13 axis

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Lung adenocarcinoma (LUAD) is one of the most common cancers with high morbidity and mortality worldwide. Long non-coding RNAs (lncRNAs) se......

Deep vein thrombosis in acute respiratory distress syndrome caused by bacterial pneumonia

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by acute hypoxaemia, and few studies have reported the inci......

Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Establishment of a mouse model is important for investigating the mechanism of chronic obstructive pulmonary disease (COPD). In this study,......

The value of transbronchial lung biopsy in the diagnosis of lymphangioleiomyomatosis

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Transbronchial lung biopsy (TBLB) in the diagnosis of lymphangioleiomyomatosis (LAM) is not a common approach, although TBLB is often perfo......

LncRNA LINC00520 aggravates cell proliferation and migration in lung adenocarcinoma via a positive feedback loop

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

Background Lung adenocarcinoma (LUAD) is the most common histological subtype of primary lung cancer. To identify the biomarker of diagnosis for LUAD ......

FSTL1 aggravates cigarette smoke-induced airway inflammation and airway remodeling by regulating autophagy

期刊: BMC PULMONARY MEDICINE, 2021; 21 (1)

BackgroundCigarette smoke (CS) is a major risk factor for Chronic Obstructive Pulmonary Disease (COPD). Follistatin-like protein 1 (FSTL1), a critical......

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