期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Gastric cancer (GC) is highly heterogeneous in the stromal and immune microenvironment, genome instability (GI), and oncogenic signatures. However, a ......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Histone methyltransferase SETD2 plays a critical role in maintaining genomic integrity and stability. Here, we investigated the characteristics of SET......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Encapsulated papillary carcinoma (EPC) of the breast is a rare subtype of tumor. To date, the genetic abnormalities underlying EPC remain elusive. The......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
The efficacy of immunotherapy is largely patient-specific due to heterogeneity in tumors. Combining statistic power from a variety of immunotherapies ......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Cancer-associated fibroblasts (CAFs) play significant roles in drug resistance through different ways. Antitumor therapies, including molecular target......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
The association between genetic variations and immunotherapy benefit has been widely recognized, while such evidence in gastrointestinal cancer remain......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Pancreatic ductal adenocarcinoma (PDAC), characterized by dense desmoplastic stroma laid down by pancreatic stellate cells (PSC), has no reliable diag......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Gliomas can be classified into five molecular groups based on the status of IDH mutation, 1p/19q codeletion, and TERT promoter mutation, whereas they ......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
An emerging body of evidence has recently recognized the coexistence of epithelial-mesenchymal transition (EMT) and immune response. However, a system......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
While next-generation sequencing (NGS) is used to guide therapy in patients with metastatic lung adenocarcinoma (LUAD), use of NGS to determine pathol......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
The epichaperome is a new cancer target composed of hyperconnected networks of chaperome members that facilitate cell survival. Cancers with an altere......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
The genetic architecture of non-small cell lung cancer (NSCLC) is relevant to smoking status. However, the genetic contribution of long-term smoking c......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Targeting mutant BRAF in patients with melanomas harboring this oncogene has been highly successful as a first-line treatment, but other mutations may......
期刊： NPJ PRECISION ONCOLOGY, 2021; 5 (1)
Angiosarcomas are a rare subtype of soft-tissue sarcomas which exhibit aggressive clinical phenotypes with limited treatment options and poor outcomes......
