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Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts

期刊: LANCET NEUROLOGY, 2021; 20 (6)

Background Post-stroke cognitive impairment (PSCI) occurs in approximately half of people in the first year after stroke. Infarct location is a potent......

Biomarkers of conversion to alpha-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder

期刊: LANCET NEUROLOGY, 2021; 20 (8)

Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly regarded as being in the early stages of a progressive neurodege......

Epilepsy in China: major progress in the past two decades

期刊: LANCET NEUROLOGY, 2021; 20 (4)

China has approximately 10 million people with epilepsy. There is a vast epilepsy treatment gap in China, mainly driven by deficiencies in health-care......

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study

期刊: LANCET NEUROLOGY, 2021; 20 (2)

Background The genetic basis of variation in the progression of primary tauopathies has not been determined. We aimed to identify genetic determinants......

Dementia in China: epidemiology, clinical management, and research advances

期刊: LANCET NEUROLOGY, 2020; 19 (1)

China has the largest population of patients with dementia in the world, imposing a heavy burden on the public and health care systems. More than 100 ......

Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial

期刊: LANCET NEUROLOGY, 2020; 19 (2)

Background Previous randomised trials have shown an overwhelming benefit of mechanical thrombectomy for treating patients with stroke caused by large ......

The characterisation of subjective cognitive decline

期刊: LANCET NEUROLOGY, 2020; 19 (3)

A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired ......

Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial

期刊: LANCET NEUROLOGY, 2020; 19 (5)

Background Azathioprine is used as a first-line treatment to prevent relapses of neuromyelitis optica spectrum disorder (NMOSD). Tocilizumab has been ......

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