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Serum Metabolomics Identifies Dysregulated Pathways and Potential Metabolic Biomarkers for Hyperuricemia and Gout

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (9)

Objective. To systematically profile metabolic alterations and dysregulated metabolic pathways in hyperuricemia and gout, and to identify potential me......

Aim2 Couples With Ube2i for Sumoylation-Mediated Repression of Interferon Signatures in Systemic Lupus Erythematosus

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (8)

Objective Systemic lupus erythematosus (SLE) involves kidney damage, and the inflammasome-caspase-1 axis has been demonstrated to promote renal pathog......

Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (8)

Objective Collectin 11 (CL-11) is a soluble C-type lectin, a mediator of innate immunity. Its role in autoimmune disorders is unknown. We undertook th......

Association of the Leukocyte Immunoglobulin-like Receptor A3 Gene With Neutrophil Activation and Disease Susceptibility in Adult-Onset Still's Disease

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (6)

Objective Adult-onset Still's disease (AOSD) is a severe autoinflammatory disease. Neutrophil activation with enhanced neutrophil extracellular trap (......

Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (6)

Objective To investigate the functional consequences of the single-nucleotide polymorphism rs4648889 in a putative enhancer upstream of the RUNX3 prom......

Association Between Gut Microbiota and Symptomatic Hand Osteoarthritis: Data From the Xiangya Osteoarthritis Study

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (9)

Objective. Systemic inflammatory factors have been implicated in symptomatic hand osteoarthritis (OA). Gut microbiome dysbiosis promotes systemic infl......

Lifetime Risks, Life Expectancy, and Health Care Expenditures for Rheumatoid Arthritis: A Nationwide Cohort Followed Up From 2003 to 2016

期刊: ARTHRITIS & RHEUMATOLOGY, ; ()

Objective This study was undertaken to estimate the cumulative incidence rate of rheumatoid arthritis (RA) in the Taiwanese population ages 16-84 year......

Association of Urinary Matrix Metalloproteinase 7 Levels With Incident Renal Flare in Lupus Nephritis

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (2)

Objective. Flares of lupus nephritis (LN) are frequent and associated with impaired renal prognosis. One major management obstacle in LN flare is the ......

Efficacy of Intensive Acupuncture Versus Sham Acupuncture in Knee Osteoarthritis: A Randomized Controlled Trial

期刊: ARTHRITIS & RHEUMATOLOGY, 2021; 73 (3)

Objective. To assess the efficacy of intensive acupuncture (3 times weekly for 8 weeks) versus sham acupuncture for knee osteoarthritis (OA). Methods.......

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