筛选条件 共查询到500条结果
排序方式
Hydrogen Peroxide-Activated Nitric Oxide-Releasing Vancomycin-Loaded Electrostatic Complexation for Efficient Elimination of Methicillin-Resistant Staphylococcus aureus Abscesses

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (1)

The treatment of subcutaneous abscesses has been greatly hindered due to the spread of drug-resistant strains such as methicillin-resistant Staphyloco......

GATA3 Encapsulated by Tumor-Associated Macrophage-Derived Extracellular Vesicles Promotes Immune Escape and Chemotherapy Resistance of Ovarian Cancer Cells by Upregulating the CD24/Siglec-10 Axis

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (2)

Tumor-associated macrophages (TAMs) possess great potential in the development of ovarian cancer (OC). Aberrant GATA-binding protein-3 (GATA3) express......

A Meta-analysis on the Effectiveness of Extracellular Vesicles as Nanosystems for Targeted Delivery of Anticancer Drugs

期刊: MOLECULAR PHARMACEUTICS, 2023; ()

While the efficacy of anticancer drugs is hampered by low bioavailability and systemic toxicity, the uncertainty remains whether encapsulation of thes......

The Chemistry of Creating Chemically Programmed Antibodies (cPAbs): Site-Specific Bioconjugation of Small Molecules

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (2)

Small-molecule drugs have been employed for years as therapeutics in the pharmaceutical industry. However, small-molecule drugs typically have short i......

Theoretical and Experimental Investigation of Autoxidation Propensity of Selected Drugs in Solution State

期刊: MOLECULAR PHARMACEUTICS, 2023; ()

The C-H bond dissociation energy (BDE) of drug molecules is often used to estimate their relative propensities to undergo autoxidation. BDE calculatio......

Using Prenucleation Aggregation of Caffeine-Benzoic Acid as a Rapid Indication of Co-crystallization from Solutions

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (4)

Co-crystal design is a convenient way to remedy the poor biopharmaceutical properties of drugs. Most studies focus on experimental co-crystal screenin......

Development of Edaravone Ionic Liquids and Their Application for the Treatment of Cerebral Ischemia/Reperfusion Injury

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (6)

Preparation of the ionic liquid (IL) form of active pharmaceutical ingredients (APIs), termed API-IL, has attracted attention because it can improve u......

Complexation of Fluorofenidone by Cucurbit[7]uril and β-Cyclodextrin: Keto-Enol Tautomerization to Enhance the Solubility

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (9)

This study is designed to compare drug encapsulation by cucurbit[7]uril and beta-cyclodextrin, using fluorofenidone as a model drug. Single-crystal X-......

Study on Sulfamethoxazole-Piperazine Salt: A Mechanistic Insight into Simultaneous Improvement of Physicochemical Properties

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (10)

Multidrug salts represent more than one drug in a crystal lattice and thus could be used to deliver multiple drugs in a single dose. It showcases uniq......

Current Advances in Nanotheranostics for Molecular Imaging and Therapy of Cardiovascular Disorders

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (10)

Cardiovascular diseases (CVDs) refer to a collection of conditions characterized by abnormalities in the cardiovascular system. They are a global prob......

Preparation of Cubosomes with Improved Colloidal and Structural Stability Using a Gemini Surfactant

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (10)

Cubosomes are nanoparticles with bicontinuous cubic internal nanostructures that have been considered for use in drug delivery systems (DDS). However,......

The Transformative Potential of Lipid Nanoparticle-Protein Corona for Next-Generation Vaccines and Therapeutics

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (11)

The integration of the lipid nanoparticle (LNP)-protein corona as a pioneering approach for the development of vaccines against the present and future......

Transferrin Receptor-Targeted Iduronate-2-sulfatase Penetrates the Blood-Retinal Barrier and Improves Retinopathy in Mucopolysaccharidosis II Mice

期刊: MOLECULAR PHARMACEUTICS, 2023; 20 (11)

Mucopolysaccharidoses (MPSs) make up a group of lysosomal storage diseases characterized by the aberrant accumulation of glycosaminoglycans throughout......

共500条页码: 1/34页15条/页