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Improved clinical outcomes of tocilizumab versus cyclophosphamide for IgG4-related disease: insights from a prospective IgG4-related disease registry

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Objective: To compare the clinical outcomes of patients with active immunoglobulin G (IgG) 4 related disease (IgG4-RD) receiving tocilizumab versus th......

EZH2 is involved in psoriasis progression by impairing miR-125a-5p inhibition of SFMBT1 and leading to inhibition of the TGF beta/SMAD pathway

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Aims: In this study, we aimed to decipher the impact of enhancer of zeste homolog 2 (EZH2) in psoriasis as well as the underlying mechanism. Methods: ......

A retrospective comparative study on arthroscopic suture anchors repair and tendon debridement versus arthroscopic tendon debridement for treatment of recalcitrant lateral epicondylitis

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Aim: To compare the outcomes between the arthroscopic debridement of the extensor carpi radialis brevis (ECRB) tendon alone and repairs to the ECRB te......

Perioperative management with biologics on severe aortic valve regurgitation caused by Behcet syndrome: the experience from a single center

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background: To investigate the efficacy and safety of biologics in the perioperative management of severe aortic valve regurgitation (AR) caused by Be......

KDM4C contributes to cytarabine resistance in acute myeloid leukemia via regulating the miR-328-3p/CCND2 axis through MALAT1

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Aims: Acute myeloid leukemia (AML) is an aggressive hematologic neoplasm, in which relapse due to drug resistance is the main cause for treatment fail......

The influence of delayed treatment due to COVID-19 on patients with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Purpose: To explore the impact of coronavirus disease 2019 (COVID-19) on the prognosis of patients with neovascular age-related macular degeneration (......

Mesenchymal stem cell-based treatment in autoimmune liver diseases: underlying roles, advantages and challenges

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Autoimmune liver disease (AILD) is a series of chronic liver diseases with abnormal immune responses, including autoimmune hepatitis (AIH), primary bi......

Sitagliptin on carotid intima-media thickness in type 2 diabetes and hyperuricemia patients: a subgroup analysis of the PROLOGUE study

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background and Aims: Studies have shown that dipeptidyl peptidase-4 (DDP-4) inhibitors have anti-atherosclerotic effects. However, in the PROLOGUE stu......

Steatosis grading consistency between controlled attenuation parameter and MRI-PDFF in monitoring metabolic associated fatty liver disease

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background: The consistency in steatosis grading between magnetic resonance imaging-based proton density fat fraction (MRI-PDFF) and controlled attenu......

A cross-sectional study: an assessment of low muscle mass and osteoporosis in type 2 diabetes mellitus patients with a high glycated hemoglobin level

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background: Low muscle mass and osteoporosis are commonly observed in individuals with type 2 diabetes mellitus (T2DM). We investigated the prevalence......

The effects of vertebral rotation on the position of the aorta relative to the spine in patients with adult degenerative scoliosis

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Aims: This study aimed to explore the effects of vertebral rotation on the position of the aorta relative to the thracolumbar and lumbar spine, and to......

Non-alcoholic fatty liver disease is associated with increased risk of chronic kidney disease

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background and Aims: Whether non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of incident chronic kidney disease (CKD) i......

Optimal treatment strategies for coronary artery disease in patients with advanced kidney disease: a meta-analysis

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background: Coronary artery disease (CAD) is the leading cause of death in advanced kidney disease. However, its best treatment has not been determine......

Meta-analysis of the association between sclerostin level and adverse clinical outcomes in patients undergoing maintenance haemodialysis

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background: Studies regarding the relationship of sclerostin (Scl) with clinical outcomes in patients undergoing maintenance haemodialysis have yielde......

MicroRNA-21 from bone marrow mesenchymal stem cell-derived extracellular vesicles targets TET1 to suppress KLF4 and alleviate rheumatoid arthritis

期刊: THERAPEUTIC ADVANCES IN CHRONIC DISEASE, 2021; 12 ()

Background: Accumulating evidence has demonstrated that bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles (EVs) can be used ef......

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