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Infectious Complications in Severe Acute Pancreatitis: Pathogens, Drug Resistance, and Status of Nosocomial Infection in a University-Affiliated Teaching Hospital

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (7)

Background Secondary infection is an important factor affecting mortality and quality of life in patients with severe acute pancreatitis. The characte......

Transcriptomic Profiling Identifies Novel Hepatic and Intestinal Genes Following Chronic Plus Binge Ethanol Feeding in Mice

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (12)

Background Alcohol-associated liver disease accounts for half of cirrhosis-related deaths worldwide. The spectrum of disease varies from simple steato......

Early Rapid Fluid Therapy Is Associated with Increased Rate of Noninvasive Positive-Pressure Ventilation in Hemoconcentrated Patients with Severe Acute Pancreatitis

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (9)

Background/Aims Hematocrit is a widely used biomarker to guide early fluid therapy for patients with acute pancreatitis (AP), but there is controversy......

Predictors for Small Bowel Stenosis in Balloon-Assisted Enteroscopy

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (9)

Background Predictors besides symptoms of obstruction indicating small bowel stenosis are little known. Aims To detect predictors of small bowel steno......

Prognostic Factors for Acute Transjugular Intrahepatic Portosystemic Shunt Occlusion Using Expanded Polytetrafluoroethylene-Covered Stent

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Background The expanded polytetrafluoroethylene (ePTFE)-covered stent has been widely used in the transjugular intrahepatic portosystemic shunt (TIPS)......

RP11-81H3.2 Acts as an Oncogene via microRNA-490-3p Inhibition and Consequential Tankyrase 2 Up-Regulation in Hepatocellular Carcinoma

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Background Hepatocellular carcinoma (HCC) is a serious threat to human lives and is usually diagnosed at the late stages. Recently, there has been a r......

Astragaloside IV Synergizes with Ferulic Acid to Alleviate Hepatic Fibrosis in Bile Duct-Ligated Cirrhotic Rats

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Background Due to the multi-factorial etiology of hepatic fibrosis, multi-target therapeutics based on combinatory drugs is known to be a promising st......

Effects of Connexin 32-Mediated Lung Inflammation Resolution During Liver Ischemia Reperfusion

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Background Hepatic ischemia reperfusion (HIR) leads to a lung inflammatory response and subsequent pulmonary barrier dysfunction. The gap junction com......

HoxC6 Functions as an Oncogene and Isoform HoxC6-2 May Play the Primary Role in Gastric Carcinogenesis

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Purpose Based on previous researches of HoxC6, this study aims to investigate the expression levels of isoforms HoxC6-1 and HoxC6-2 and to explore the......

MetaDE-Based Analysis of circRNA Expression Profiles Involved in Gastric Cancer

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Background Circular RNAs (circRNAs) could play carcinogenic roles in gastric cancer (GC) and have potential to be biomarkers for GC early diagnosis, w......

iASPP-Mediated ROS Inhibition Drives 5-Fu Resistance Dependent on Nrf2 Antioxidative Signaling Pathway in Gastric Adenocarcinoma

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Aims Inhibitor for the apoptosis-stimulating protein of p53 (iASPP) has been reported to be correlated with 5-fluorouracil (5-Fu) resistance in renal ......

LncRNA ANCR Promotes Invasion and Migration of Gastric Cancer by Regulating FoxO1 Expression to Inhibit Macrophage M1 Polarization

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Background Long non-coding RNAs (LncRNAs) are closely related to the occurrence of cancer, but its mechanism in gastric cancer (GC) is still largely u......

Down-Regulation of miR-2053 Inhibits the Development and Progression of Esophageal Carcinoma by Targeting Fyn-Related Kinase (FRK)

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Background MicroRNAs (miRNAs) play essential roles in the regulation and pathophysiology of various types of cancers including esophageal carcinoma (E......

Silencing of Long Noncoding RNA SNHG6 Inhibits Esophageal Squamous Cell Carcinoma Progression via miR-186-5p/HIF1 alpha Axis

期刊: DIGESTIVE DISEASES AND SCIENCES, 2020; 65 (10)

Aims Long noncoding RNA (lncRNA) small nucleolar RNA host gene 6 (SNHG6) has been shown to be upregulated in esophageal squamous cell carcinoma (ESCC)......

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