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Liraglutide increases islet Ca2+ oscillation frequency and insulin secretion by activating hyperpolarization-activated cyclic nucleotide-gated channels

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (9)

Aim To determine whether hyperpolarization-activated cyclic nucleotide-gated (HCN) channels impact glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) m......

JIF:6.092

Glucagon-like peptide-1 effect on beta-cell function varies according to diabetes remission status after Roux-en-Y gastric bypass

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (11)

Aims The contribution of endogenous glucagon-like peptide (GLP)-1 to beta-cell function after Roux-en-Y gastric bypass surgery (RYGB) is well establis......

JIF:6.092

Low-dose hydralazine reduces albuminuria and glomerulosclerosis in a mouse model of obesity-related chronic kidney disease

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (10)

Aim To determine, using a mouse model of obesity, whether low-dose hydralazine prevents obesity-related chronic kidney disease (CKD). Methods From 8 w......

JIF:6.092

Separate and combined effect of visit-to-visit glycaemic variability and mean fasting blood glucose level on all-cause mortality in patients with type 2 diabetes: A population-based cohort study

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (12)

Aims To assess the independent and combined impacts of visit-to-visit fasting blood glucose variability (VVV-FBG) and mean fasting blood glucose level......

JIF:6.092

A clinical overview of non-alcoholic fatty liver disease: A guide to diagnosis, the clinical features, and complications-What the non-specialist needs to know

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 ()

Non-alcoholic fatty liver disease (NAFLD) has a rapidly rising prevalence worldwide and is the most common cause of liver disease in developed countri......

JIF:6.092

A single bout of cycling exercise induces nucleosome repositioning in the skeletal muscle of lean and overweight/obese individuals

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (1)

Aim: To compare the molecular and metabolic effects of a single exercise bout in the skeletal muscle between lean and overweight/obese (Ov/Ob) individ......

JIF:6.092

Weight loss interventions and nonalcoholic fatty liver disease: Optimizing liver outcomes

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 ()

The growth in prevalence of obesity, type 2 diabetes and nonalcoholic fatty liver disease (NAFLD) has become one of the most important global health c......

JIF:6.092

Effect of upper gastrointestinal disease on the pharmacokinetics of oral semaglutide in subjects with type 2 diabetes

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (4)

Aim To investigate whether upper gastrointestinal (GI) disease has any effect on the exposure of oral semaglutide, an important consideration given th......

JIF:6.092

Cost of healthcare utilization associated with incident cardiovascular and renal disease in individuals with type 2 diabetes: A multinational, observational study across 12 countries

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (7)

Aim To examine how the development of cardiovascular and renal disease (CVRD) translates to hospital healthcare costs in individuals with type 2 diabe......

JIF:6.092

Prediabetes diagnosis is associated with the progression of coronary artery calcification: The Kangbuk Samsung Health Study

期刊: DIABETES OBESITY & METABOLISM, 2022; 24 (11)

Aim To investigate the associations between prediabetes defined by different diagnostic criteria and coronary artery calcification (CAC) and its progr......

JIF:6.092

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