期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 203 ()
Elevated expression of the receptor for advanced-glycation endproducts (RAGE) in cardiac tissue is well-known in the elderly, in diabetes mellitus, an......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 204 ()
The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented clinical and socio-economic worldwide relevance. The case fatality rate......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 206 ()
Among the age-associated changes in the immune system, the most evident is the decrease in proliferative responses of lymphocytes to mitogenic stimuli......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 208 ()
Leptin and ROS are implicated in the regulation of inflammatory pathways including NLRP3-inflammasome. We investigated the functional link between lep......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 203 ()
A higher number of laboratory measurements is associated with mortality in patients admitted to hospital, but is not part of the frailty index based o......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 201 ()
Accelerated biological aging contributes to the evolution of cardiovascular disease. However, its influence on subclinical organ damage remains unclea......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 203 ()
Introduction: This review examined the impact of ageing, fall history and exercise on postural reflexes and adaptation to unpredictable perturbations.......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 204 ()
Huntington disease (HD) is a neurodegenerative disorder produced by an expansion of CAG repeats in the HTT gene. Patients of HD show involuntary movem......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 202 ()
The paper provides a comprehensive and foundational mechanistic framework of hormesis that establishes its centrality in medicine and public health. T......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 202 ()
The stratification of mortality risk in COVID-19 patients remains extremely challenging for physicians, especially in older patients. Innovative minim......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 204 ()
Geroprotection is defined as protection from the adverse effects of aging. The need for geroprotection implies changes towards individually tailored i......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 206 ()
DNA methylation (DNAm) overwrites information about multiple extrinsic factors on the genome. Age is one of these factors. Age causes characteristic D......
期刊: MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 207 ()
Alzheimer's disease (AD) is an evolving challenge that places an enormous burden on families and society. The presence of obvious brain beta-amyloid (......