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Transfusion of fresh washed platelets does not prevent experimental polymicrobial-induced septic shock in mice

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (2)

Introduction The specific role of platelets during sepsis is not yet fully understood, probably related to the paradox of platelets being potentially ......

JIF:3.961

Removal of single-site N-linked glycans on factor VIII alters binding of domain-specific monoclonal antibodies

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (3)

Background A portion of individuals with hemophilia A develop neutralizing antibodies called inhibitors to glycoprotein factor VIII (FVIII). There are......

JIF:3.961

Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (5)

Background Human and mouse platelets both express protease-activated receptor (PAR) 4 but sequence alignment reveals differences in several functional......

JIF:3.961

Frequency and utility of bone marrow examination in relapsed/refractory immune thrombocytopenia

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (9)

Background The diagnosis of immune thrombocytopenia (ITP) is one of exclusion. Although guidelines recommend against routine bone marrow examination (......

JIF:3.961

Temporal presentations of heparin-induced thrombocytopenia following cardiac surgery: A single-center, retrospective cohort study

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (11)

Background Heparin-induced thrombocytopenia (HIT) is an important adverse drug reaction that can occur postcardiac surgery. Preoperative exposure to u......

JIF:3.961

Exclusively breastmilk-fed preterm infants are at high risk of developing subclinical vitamin K deficiency despite intramuscular prophylaxis at birth

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (12)

Background There is near-global consensus that all newborns be given parenteral vitamin K-1 (VK1) at birth as prophylaxis against VK deficiency bleedi......

JIF:3.961

Awareness of venous thromboembolism among patients with cancer: Preliminary findings from a global initiative for World Thrombosis Day

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (12)

Background Cancer-associated venous thromboembolism (CAT) has detrimental impact on patients' clinical outcomes and quality of life. Data on CAT educa......

JIF:3.961

Desialylation of O-glycans activates von Willebrand factor by destabilizing its autoinhibitory module

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (1)

Background The binding of the A1 domain of von Willebrand factor (VWF) to platelet receptor glycoprotein (GP)Ib alpha defines the VWF activity in hemo......

JIF:3.961

Podoplanin promotes tumor growth, platelet aggregation, and venous thrombosis in murine models of ovarian cancer

期刊: JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2022; 20 (1)

Background Podoplanin (PDPN) is a sialylated membrane glycoprotein that binds to C-type lectin-like receptor 2 on platelets resulting in platelet acti......

JIF:3.961

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