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Case Report: Central Nervous System Immune Reconstitution Inflammatory Syndrome Related to Bacterial Meningitis

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Central nervous system immune reconstitution inflammatory syndrome (CNS-IRIS) describes clinical characteristics that may be observed in previously im......

The Functional and Antiviral Activity of Interferon Alpha-Inducible IFI6 Against Hepatitis B Virus Replication and Gene Expression

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Hepatitis B virus is an enveloped DNA virus, that infects more than three hundred and sixty million people worldwide and leads to severe chronic liver......

Paroxysmal Sympathetic Hyperactivity in Severe Anti-N-Methyl-d-Aspartate Receptor Encephalitis: A Single Center Retrospective Observational Study

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Background Paroxysmal sympathetic hyperactivity (PSH) is a disorder with excessive sympathetic activity commonly recognized in patients with acquired ......

Tributyrin Plays an Important Role in Regulating the Growth and Health Status of Juvenile Blunt Snout Bream (Megalobrama amblycephala), as Evidenced by Pathological Examination

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

The present study aimed to assess the role of tributyrin (TB) in regulating the growth and health status of juvenile blunt snout bream (Megalobrama am......

Robust Prediction of Immune Checkpoint Inhibition Therapy for Non-Small Cell Lung Cancer

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Background The development of immune checkpoint inhibitors (ICIs) is a revolutionary milestone in the field of immune-oncology. However, the low respo......

Tr1 Cells as a Key Regulator for Maintaining Immune Homeostasis in Transplantation

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

The immune system is composed of effectors and regulators. Type 1 regulatory T (Tr1) cells are classified as a distinct subset of T cells, and they se......

The Importance of Glycans of Viral and Host Proteins in Enveloped Virus Infection

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Animal viruses are parasites of animal cells that have characteristics such as heredity and replication. Viruses can be divided into non-enveloped and......

Erythrocyte Adhesion of Merozoite Surface Antigen 2c1 Expressed During Extracellular Stages of Babesia orientalis

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Babesia orientalis, a major infectious agent of water buffalo hemolytic babesiosis, is transmitted by Rhipicephalus haemaphysaloides. However, no effe......

Macrophage Heterogeneity in Kidney Injury and Fibrosis

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Kidney macrophages are central in kidney disease pathogenesis and have therapeutic potential in preventing tissue injury and fibrosis. Recent studies ......

Galectin-Receptor Interactions Regulates Cardiac Pathology Caused by Trichinella spiralis Infection

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

The parasitic nematode Trichinella spiralis causes trichinellosis, a serious food-borne parasitic zoonosis worldwide. Infection with T. spiralis may a......

Immunodominance of Epitopes and Protective Efficacy of HI Antigen Are Differentially Altered Using Different Adjuvants in a Mouse Model of Staphylococcus aureus Bacteremia

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

HI, a fusion protein that consists of the alpha-toxin (Hla) and the N2 domain of iron surface determinant B (IsdB), is one of the antigens in the prev......

STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

STING (Stimulator of interferon genes) is known as an important adaptor protein or direct sensor in the detection of nucleotide originating from patho......

High Mobility Group Box 1 Contributes to the Acute Rejection of Liver Allografts by Activating Dendritic Cells

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Acute rejection induced by the recognition of donor alloantigens by recipient T cells leads to graft failure in liver transplant recipients. The role ......

A Novel Immune-Related Seventeen-Gene Signature for Predicting Early Stage Lung Squamous Cell Carcinoma Prognosis

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

With the increasingly early stage lung squamous cell carcinoma (LUSC) being discovered, there is an urgent need for a comprehensive analysis of the pr......

Immune Cells in the BBB Disruption After Acute Ischemic Stroke: Targets for Immune Therapy?

期刊: FRONTIERS IN IMMUNOLOGY, 2021; 12 ()

Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute ischemic stroke (AIS), resulting in devastating malignant bra......

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