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Most degenerative cervical myelopathy remains undiagnosed, particularly amongst the elderly: modelling the prevalence of degenerative cervical myelopathy in the United Kingdom

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (1)

Background Degenerative cervical myelopathy (DCM) is a poorly recognised form of spinal cord injury which arises when degenerative changes in the cerv......

Discontinuation of second- versus first-line disease-modifying treatment in middle-aged patients with multiple sclerosis

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (1)

Background and purpose There has been scant research on the consequences of discontinuing second-line disease-modifying treatment (DMT) in middle-aged......

Use of remote monitoring and integrated platform for the evaluation of sleep quality in adult-onset idiopathic cervical dystonia

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (3)

Background Up to 70% of individuals diagnosed with adult-onset idiopathic focal cervical dystonia (AOIFCD) report difficulties with sleep. Larger coho......

Clinical and MRI features of gait and balance disorders in neurodegenerative diseases

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (3)

Gait and balance disorders are common signs in several neurodegenerative diseases such as Parkinson's disease, atypical parkinsonism, idiopathic norma......

Intrinsic brain functional connectivity predicts treatment-related motor complications in early Parkinson's disease patients

期刊: JOURNAL OF NEUROLOGY, 2023; ()

BackgroundTreatment-related motor complications may develop progressively over the course of Parkinson's disease (PD).ObjectiveWe investigated intrins......

Mitochondrial myopathy without extraocular muscle involvement: a unique clinicopathologic profile

期刊: JOURNAL OF NEUROLOGY, 2023; ()

Objective Mitochondrial myopathy without extraocular muscles involvement (MiMy) represents a distinct form of mitochondrial disorder predominantly aff......

Weaning and extubation failure in myasthenic crisis: a multicenter analysis

期刊: JOURNAL OF NEUROLOGY, 2023; ()

Myasthenic crisis (MC) requiring mechanical ventilation is a serious complication of myasthenia gravis (MG). Here we analyze the frequency and risk fa......

Evaluation of drivers of treatment switch in relapsing multiple sclerosis: a study from the Italian MS Registry

期刊: JOURNAL OF NEUROLOGY, 2023; ()

Background Active relapsing-remitting (RR) and secondary progressive (SP) multiple sclerosis (MS) are currently defined as relapsing MS (RMS). The aim......

Salivary Aβ1-42 may be a quick-tested biomarker for clinical use in Alzheimer's disease: a meta-analysis

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (4)

Objective Alzheimer's disease (AD) is the most prevalent form of dementia among the aging population. Cumulative studies aim to find non-invasive biom......

DBS in tremor with dystonia: VIM, GPi or both? A review of the literature and considerations from a single-center experience

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (4)

BackgroundDeep brain stimulation (DBS) is an established treatment for dystonia and tremor. However, there is no consensus about the best surgical tar......

Temporal evolution of new T1-weighted hypo-intense lesions and central brain atrophy in patients with a first clinical demyelinating event treated with subcutaneous interferon β-1a

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (4)

Objective Evaluate the effect of subcutaneous interferon ss-1a (sc IFN ss-1a) versus placebo on the evolution of T1-weighted MRI lesions and central b......

Common neural correlates of vestibular stimulation and fear learning: an fMRI meta-analysis

期刊: JOURNAL OF NEUROLOGY, 2023; 270 (4)

BackgroundA bidirectional functional link between vestibular and fear-related disorders has been previously suggested.ObjectiveTo test a potential ove......

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