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Ex Vivo Expansion and Drug Sensitivity Profiling of Circulating Tumor Cells from Patients with Small Cell Lung Cancer

期刊: CANCERS, 2020; 12 (11)

Simple Summary Small cell lung cancer (SCLC) is an overly aggressive cancer characterized by rapid growth, early metastatic spread, and consequently r......

Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8(+) T Cells in Non-Melanoma Cancers Compared to Melanoma

期刊: CANCERS, 2020; 12 (11)

Simple Summary Human tumors are often infiltrated by T cells; however, it remains unclear what proportion of T cells infiltrating tumors are bystander......

Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity

期刊: CANCERS, 2020; 12 (11)

Simple Summary DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has recently attracted increasing attention due to the emerging novel functio......

Quantifying the Effect of Financial Burden on Health-Related Quality of Life among Patients with Non-Hodgkin's Lymphomas

期刊: CANCERS, 2020; 12 (11)

Simple Summary Financial burdens result from the growing out-of-pocket costs associated with cancer care to help patients regain physical and psycholo......

Mifepristone Treatment Promotes Testicular Leydig Cell Tumor Progression in Transgenic Mice

期刊: CANCERS, 2020; 12 (11)

Simple Summary Recently, the antiprogestin activity of selective progesterone receptor (PR) modulator mifepristone (MF) has proven unsuccessful as a p......

BH3 Mimetics for the Treatment of B-Cell Malignancies-Insights and Lessons from the Clinic

期刊: CANCERS, 2020; 12 (11)

Simple Summary B-cell malignancies, including chronic lymphocytic leukemia (CLL), non-Hodgkin lymphoma (NHL), and plasma cell dyscrasias, are signific......

The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment

期刊: CANCERS, 2020; 12 (11)

Simple Summary The unique characteristics of tumor energy metabolism (highly dependent on aerobic glycolysis, namely, the Warburg effect) make it an i......

AGTR1 Is Overexpressed in Neuroendocrine Neoplasms, Regulates Secretion and May Potentially Serve as a Target for Molecular Imaging and Therapy

期刊: CANCERS, 2020; 12 (11)

Simple Summary Clinical management of neuroendocrine neoplasms (NEN), especially of those low in target molecules such as somatostatin receptors, may ......

Growth Factor Receptor Expression in Oropharyngeal Squamous Cell Cancer: Her1-4 and c-Met in Conjunction with the Clinical Features and Human Papillomavirus (p16) Status

期刊: CANCERS, 2020; 12 (11)

Simple Summary Growth factor expression is a negative prognostic factor in head and neck squamous cell carcinoma (HNSCC). Targeted therapy has a limit......

Cold Atmospheric Plasma: A Promising Controller of Cancer Cell States

期刊: CANCERS, 2020; 12 (11)

Simple Summary Cancer treatment is complicated by the distinct phenotypic attractor states in which cancer cells exist within individual tumors, and i......

The Role of Long Non-Coding RNA NNT-AS1 in Neoplastic Disease

期刊: CANCERS, 2020; 12 (11)

Simple Summary Nicotinamide nucleotide transhydrogenase-antisense 1 (NNT-AS1), which is a newly-discovered long non-coding RNA (lncRNA), has been foun......

Transforming Growth Factor-beta: A Multifunctional Regulator of Cancer Immunity

期刊: CANCERS, 2020; 12 (11)

Simple Summary Transforming growth factor beta (TGF-beta) is a multifunctional cytokine that can restrict cancer onset but also promote cancer progres......

Biomimetic Upconversion Nanoparticles and Gold Nanoparticles for Novel Simultaneous Dual-Modal Imaging-Guided Photothermal Therapy of Cancer

期刊: CANCERS, 2020; 12 (11)

Simple Summary Multimodal imaging systems with high registration accuracy and molecular agents with highly specific targeting capacity are vital for i......

LDOC1 Suppresses Microbe-Induced Production of IL-1 beta in Human Normal and Cancerous Oral Cells through the PI3K/Akt/GSK-3 beta Axis

期刊: CANCERS, 2020; 12 (11)

Simple Summary Oral microbes often proliferate due to poor oral hygiene (POH). POH is associated with OSCC (oral squamous cell carcinoma). We investig......

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