期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (11)
NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome has been implicated in a variety of inflammatory disorders, and its activation ......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (12)
We have previously shown that Mkp-1-deficient mice produce elevated TNF-alpha, IL-6, and IL-10 following systemic Escherichia coli infection, and they......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (9)
IFN-induced protein with tetratricopeptide repeats (IFITs), known as canonical IFN-stimulated genes (ISGs), play critical roles in regulating immune r......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (10)
Sepsis induces significant immune dysregulation characterized by lymphocyte apoptosis and alterations in the cytokine milieu. Because cancer patients ......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (9)
Preserving appropriate function and metabolism in regulatory T (Treg) cells is crucial for controlling immune tolerance and inflammatory responses. Ye......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (9)
Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some pat......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (10)
T cell development is predicated on the successful rearrangement of the TCR gene loci, which encode for Ag-specific receptors. Recombination-activatin......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (11)
The antiviral innate immune responses are crucial steps during host defense and must be strictly regulated, but the molecular mechanisms of control re......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (8)
CARD9 is an essential adaptor protein in antifungal innate immunity mediated by C-type lectin receptors. The activity of CARD9 is critically regulated......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (9)
White spot syndrome virus (WSSV) is a threatening pathogenic virus in shrimp culture, and at present, no effective strategy can prevent and control th......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (12)
The relatively low partial pressure of oxygen, reduced oxygen saturation, and aberrant plasma metabolites in COVID-19 may alter energy metabolism in p......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (12)
The etiology and pathology of Kawasaki disease (KD) remain elusive. Cub domain-containing protein 1 (CDCP1), a cell-surface protein that confers poor ......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (9)
The recently identified anion channel LRRC8 volume-regulated anion channels (VRACs) are heteromeric hexamers constituted with the obligate LRRC8A subu......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (12)
Although organ hypofunction and immunosuppression are life-threatening features of severe sepsis, the hypofunctioning organs and immune cells usually ......
期刊： JOURNAL OF IMMUNOLOGY, 2021; 206 (12)
The quality of T cell responses depends on the lymphocytes' ability to undergo clonal expansion, acquire effector functions, and traffic to the site o......
