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Effect of diabetes blood-stasis syndrome and Xuefu Zhuyu decoction on ERK1/2-VEGF signal pathway in rat retina Muller cells

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (8)

Aims. This research was aimed to investigate whether diabetic blood-stasis syndrome had a relationship with ERK1/2-VEGF signaling pathway in rat retin......

JIF:2.051

Investigation of clinical application of claudin 18 isoform 2 in pancreatic ductal adenocarcinoma: A retrospective analysis of 302 chinese patients

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (10)

The malignancy of pancreatic ductal adenocarcinoma (PDAC) results from high frequency of recurrence and limited effective therapies. Targeted therapy ......

JIF:2.051

Anesthetic propofol suppresses growth and metastasis of lung adenocarcinoma in vitro through downregulating circ-MEMO1-miR-485-3p-NEK4 ceRNA axis

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (12)

Background. Recently, circular RNAs (circRNAs) have been emerging as new regulators in the propofol-induced tumor-suppressive role. Here, we intended ......

JIF:2.051

Circ-SFMBT2 facilitates the malignant growth of acute myeloid leukemia cells by modulating miR-582-3p/ZBTB20 pathway

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (2)

Background. Acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy. Circular RNAs (circRNAs) play crucial roles in AML progre......

JIF:2.051

MiR-486-5p specifically suppresses SAPCD2 expression, which attenuates the aggressive phenotypes of lung adenocarcinoma cells

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (9)

Background. MiR- 486-5p expression is restrained in lung adenocarcinoma (LUAD). However, much less has been understood on its role in LUAD. We aimed t......

JIF:2.051

CircRNA circBACH1 facilitates hepatitis B virus replication and hepatoma development by regulating the miR-200a-3p/MAP3K2 axis

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (9)

Background. Hepatitis B virus (HBV) is a top contributor to hepatoma. Circular RNAs (circRNAs) have been elucidated to have a close connection with HB......

JIF:2.051

Downregulation of KIF15 inhibits the tumorigenesis of non-small-cell lung cancer via inactivating Raf/MEK/ERK signaling

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (3)

Background. Lung cancer is one of the most common causes of cancer-associated mortality worldwide. Upregulation of kinesin family member 15 (KIF15) ex......

JIF:2.051

Differential expression of Tim3 protein in colorectal cancer associated with MSI and Brafmutation

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (5)

Tim3 is a negative immune checkpoint molecule and plays a crucial part in tumor-induced immune suppression. Tim3 is a cell surface molecule expressed ......

JIF:2.051

The expression of hydrogen sulfide-producing enzymes in primary and lung metastatic osteosarcoma

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (7)

Background. Hydrogen sulfide (H2S) is a novel gas transmitter signaling molecule. H2S is synthesized by cystathionine beta-synthase (CBS), cystathioni......

JIF:2.051

MiR-124-3p attenuates brain microvascular endothelial cell injury in vitro by promoting autophagy

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (2)

Traumatic brain injury (TBI) can cause the pathological disruption of the blood-brain barrier (BBB) and associated neurological injury. Reducing the s......

JIF:2.051

Mdivi-1: a promising drug and its underlying mechanisms in the treatment of neurodegenerative diseases

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (6)

Mitochondria are energy-producing organelles, and neurons are high energy consumption cells. Therefore, mitochondrial dysfunction is a critical factor......

JIF:2.051

Circular RNA circSDHC (hsa_circ_0015004) regulates tumor growth and angiogenesis via regulating centrosomal protein 55 expression in renal cell carcinoma

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (10)

Background. Renal cell carcinoma (RCC) is the main aggressive subtype of kidney cancer. Circular RNAs have been shown to exert critical roles in RCC. ......

JIF:2.051

LncRNA SNHG15 regulates hypoxic-ischemic brain injury via miR-153-3p/SETD7 axis

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (11)

Hypoxic-ischemic encephalopathy (HIE) is a leading cause of fatality and morbidity in newborns. Long non-coding RNAs (lncRNAs) Small Nucleolar RNA Hos......

JIF:2.051

Sphingosine Kinase-1 (SPHK1) promotes inflammation in infantile pneumonia by regulating NLRP3 inflammasome and SIRT1 expression

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (12)

. Background. Infantile pneumonia is an acute inflammatory disorder of the lung caused by mycoplasma pneumonia. SPHK1 (sphingosine kinase-1) signaling......

JIF:2.051

CircRIP2 promotes NSCLC progression by sponging for miR-671-5p to regulate FOXM1 expression

期刊: HISTOLOGY AND HISTOPATHOLOGY, 2022; 37 (2)

Lot of attention had been paid to the role of circular RNAs (circRNAs) in carcinogenesis recently. However, knowledge about circRNAs in NSCLC developm......

JIF:2.051

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