期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (8)
A survey of natural metabolic pathways for C1 substrates (methane, methanol, carbon dioxide, and carbon monoxide) highlights past efforts and recent p......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (9)
The peptidyl-prolyl isomerase, Pin1, is exploited in cancer to activate oncogenes and inactivate tumor suppressors. However, despite considerable effo......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (7)
RNA molecules fold into complex structures that enable their diverse functions in cells. Recent revolutionary innovations in transcriptome-wide RNA st......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (7)
The central dogma of biology does not allow for the study of glycans using DNA sequencing. We report a liquid glycan array (LiGA) platform comprising ......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (1)
We asked a collection of chemical biologists, "What was the most exciting research achievement or technology innovation in chemical biology in the las......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (8)
Plant-based photosensors, such as the light-oxygen-voltage sensing domain 2 (LOV2) from oat phototropin 1, can be modularly wired into cell signaling ......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (8)
Protein ubiquitination shows remarkable topological and functional diversity through the polymerization of ubiquitin via different linkages. Decipheri......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (8)
The development of unnatural base pairs (UBPs) has greatly increased the information storage capacity of DNA, allowing for transcription of unnatural ......
期刊： NATURE CHEMICAL BIOLOGY, 2021; 17 (2)
Yin Yang 1 (YY1) is a transcription factor involved in gene regulation. A recent study has revealed G-quadruplex structures as novel binding targets o......
期刊： NATURE CHEMICAL BIOLOGY, ; ()
How aerobic organisms exploit inevitably generated but potentially dangerous reactive oxygen species (ROS) to benefit normal life is a fundamental bio......
期刊： NATURE CHEMICAL BIOLOGY, ; ()
The discovery of effective therapeutic treatments for cancer via cell differentiation instead of antiproliferation remains a great challenge. Cyclin-d......
期刊： NATURE CHEMICAL BIOLOGY, ; ()
Cariogenic Streptococcus mutans is known as a predominant etiological agent of dental caries due to its exceptional capacity to form biofilms. From st......
期刊： NATURE CHEMICAL BIOLOGY, ; ()
YcaO enzymes catalyze several post-translational modifications on peptide substrates, including thioamidation, which substitutes an amide oxygen with ......
期刊： NATURE CHEMICAL BIOLOGY, ; ()
Although naturally occurring catalytic RNA molecules-ribozymes-have attracted a great deal of research interest, very few have been identified in huma......
