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HOXA-AS3 induces tumor progression through the epithelial-mesenchymal transition pathway in epithelial ovarian cancer

期刊: ONCOLOGY REPORTS, 2023; 49 (3)

HOXA cluster antisense RNA 3 (HOXA-AS3) is considered to be involved in several malignancies, however, its biological function in the progression of e......

Therapeutic effects of natural polyphenols on colorectal adenomas: Focus on preclinical studies (Review)

期刊: ONCOLOGY REPORTS, 2023; 49 (6)

Colorectal adenoma (CRA) is a premalignant lesion of colorectal cancer. The current treatment is surgical resection, but CRA is prone to recurrence, a......

Aprepitant inhibits the progression of esophageal squamous cancer by blocking the truncated neurokinin-1 receptor

期刊: ONCOLOGY REPORTS, 2023; 50 (1)

Increasing evidence showed that the substance P (SP)/neurokinin-1 receptor (NK1R) complex is involved in the development of several cancers. However, ......

Advances in the protein-encoding functions of circular RNAs associated with cancer (Review)

期刊: ONCOLOGY REPORTS, 2023; 50 (2)

Circular RNAs (circRNAs) are a special class of non-coding RNAs that are widely expressed in tissues and cells. Owing to their lack of a 5 & PRIME......

Clinical outcomes of second-line chemotherapy after gemcitabine and cisplatin plus S-1 treatment for patients with advanced biliary tract cancer in the KHBO1401-3A study

期刊: ONCOLOGY REPORTS, 2023; 49 (2)

Since the completion of the KHBO1401 study, which evaluated the efficacy of the combination of gemcitabine (GEM) and cisplatin (GC) compared with GC p......

Ubiquitin-conjugating enzymes as potential biomarkers and therapeutic targets for digestive system cancers (Review)

期刊: ONCOLOGY REPORTS, 2023; 49 (3)

Digestive system cancers are the leading cause of cancer-related death worldwide due to their high morbidity and mortality rates. The current treatmen......

High-risk pathological subtype associated FAM83A-AS1 promotes malignancy and glycolysis of lung adenocarcinoma via miR-202-3p/HK2 axis

期刊: ONCOLOGY REPORTS, 2023; 49 (5)

According to the diverse cellular morphology, lung adenocarcinoma (LUAD) was classified into five pathological subtypes, referred to as follows: High-......

NONHSAG028908.3 sponges miR-34a-5p to promote growth of colorectal cancer via targeting ALDOA

期刊: ONCOLOGY REPORTS, 2023; 49 (5)

Colorectal cancer (CRC) is an aggressive tumor, whose development is considered to be modulated by certain long non-coding RNAs (lncRNAs). Therefore, ......

Recent advances and pathological mechanisms in photodynamic and sonodynamic therapy in the treatment of bone tumors (Review)

期刊: ONCOLOGY REPORTS, 2023; 50 (5)

Given the recent advances that have been made with photodynamic therapy (PDT) combined with sonodynamic therapy (SDT) (PDT/SDT; also known as SPDT), t......

Unrevealed roles of extracellular enolase-1 (ENO1) in promoting glycolysis and pro-cancer activities in multiple myeloma via hypoxia-inducible factor 1α

期刊: ONCOLOGY REPORTS, 2023; 50 (5)

The involvement of enolase-1 (ENO1), intracellularly or extracellularly, has been implicated in cancer development. Moreover, anticancer activities of......

Copper (II) complex of salicylate phenanthroline induces the apoptosis of colorectal cancer cells, including oxaliplatin-resistant cells

期刊: ONCOLOGY REPORTS, 2023; 50 (3)

Oxaliplatin (Oxa) is one of the most effective chemotherapeutic drugs used in the treatment of colorectal cancer (CRC). However, the use of this drug ......

Aggressive local therapy for de novo metastatic breast cancer: Challenges and updates (Review)

期刊: ONCOLOGY REPORTS, 2023; 50 (3)

Systemic therapy has been viewed as the mainstay for de novo metastatic breast cancer (dnMBC). However, as dnMBC is highly heterogeneous both biologic......

Extracellular vesicle-mediated RNA editing may underlie the heterogeneity and spread of hepatocellular carcinoma in human tissue and in vitro

期刊: ONCOLOGY REPORTS, 2023; 50 (5)

Extracellular vesicles (EVs) produced by various cells, including tumor cells, carry biomolecules to neighboring cells. In hepatocellular carcinoma (H......

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