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DDX04(+) Stem Cells in the Ovaries of Postmenopausal Women: Existence and Differentiation Potential

期刊: STEM CELLS, 2022; 40 (1)

Ovarian aging is a pacemaker with multiple organ dysfunction. Recently, stem cells with the ability to generate new oocytes have been identified, whic......

JIF:5.215

Gadd45g, A Novel Antidepressant Target, Mediates Metformin-Induced Neuronal Differentiation of Neural Stem Cells Via DNA Demethylation

期刊: STEM CELLS, 2022; 40 (1)

Increased neurogenesis elicits antidepressive-like effects. The antidiabetic drug metformin (Met) reportedly promotes hippocampal neurogenesis, which ......

JIF:5.215

Mst1/2 Is Necessary for Satellite Cell Differentiation to Promote Muscle Regeneration

期刊: STEM CELLS, 2022; 40 (1)

The diminished ability for muscle to regenerate is associated with aging, diabetes, and cancers. Muscle regeneration depends on the activation and dif......

JIF:5.215

Porcine Pluripotent Stem Cells Established from LCDM Medium with Characteristics Differ from Human and Mouse Extended Pluripotent Stem Cells

期刊: STEM CELLS, 2022; 40 (8)

Pluripotent stem cells (PSCs) have unlimited self-renewal and multifunctional development potential in vitro. Porcine PSCs are highly desirable due to......

JIF:5.215

Melatonin-Primed MSCs Alleviate Intrauterine Adhesions by Affecting MSC-Expressed Galectin-3 on Macrophage Polarization

期刊: STEM CELLS, 2022; 40 (10)

Intrauterine adhesion (IUA) is characterized by the presence of fibrosis in the uterine cavity. It is mainly caused by infection or trauma to the endo......

JIF:5.215

Foxp1 and Foxp4 Deletion Causes the Loss of Follicle Stem Cell Niche and Cyclic Hair Shedding by Inducing Inner Bulge Cell Apoptosis

期刊: STEM CELLS, 2022; 40 (9)

Quiescent hair follicle stem cells (HFSCs) reside in specialized bulge niche where they undergo activation and differentiation upon sensing niche-depe......

JIF:5.215

ROR2 Downregulation Activates the MSX2/NSUN2/p21 Regulatory Axis and Promotes Dental Pulp Stem Cell Senescence

期刊: STEM CELLS, 2022; 40 (3)

Cellular senescence severely limits the research and the application of dental pulp stem cells (DPSCs). A previous study conducted by our research gro......

JIF:5.215

IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation through Regulation of RUNX2 Expression and Translocation

期刊: STEM CELLS, 2022; 40 (11)

RUNX2, an important transcriptional factor for both odontoblastic and osteoblastic differentiation, is upregulated during osteoblastic differentiation......

JIF:5.215

Exosome From BMMSC Attenuates Cardiopulmonary Bypass-Induced Acute Lung Injury Via YAP/beta-Catenin Pathway: Downregulation of Pyroptosis

期刊: STEM CELLS, 2022; 40 (12)

Acute lung injury (ALI) accompanied with systemic inflammatory response is an important complication after cardiopulmonary bypass (CPB). Pyroptosis, w......

JIF:5.215

Long Noncoding RNA Lx8-SINE B2 Interacts with Eno1 to Regulate Self-Renewal and Metabolism of Embryonic Stem Cells

期刊: STEM CELLS, 2022; 40 (12)

Long noncoding RNAs (lncRNAs) emerge as important orchestrators of biological processes in embryonic stem cells (ESCs). LncRNA Lx8-SINE B2 was recentl......

JIF:5.215

DAPK1 Interacts with the p38 Isoform MAPK14, Preventing Its Nuclear Translocation and Stimulation of Bone Marrow Adipogenesis

期刊: STEM CELLS, 2022; 40 (5)

Bone marrow (BM) adipose tissue (BMAT), a unique adipose depot, plays an important role in diseases such as osteoporosis and bone metastasis. Precise ......

JIF:5.215

PD-1 Suppresses the Osteogenic and Odontogenic Differentiation of Stem Cells from Dental Apical Papilla via Targeting SHP2/NF-kappa B Axis

期刊: STEM CELLS, 2022; 40 (8)

Stem cells from the apical papilla (SCAPs) are important for tooth root development and regeneration of root dentin. Here, we examined the expression ......

JIF:5.215

Sirt1 Protects Subventricular Zone-Derived Neural Stem Cells from DNA Double-Strand Breaks and Contributes to Olfactory Function Maintenance in Aging Mice

期刊: STEM CELLS, 2022; 40 (5)

DNA damage is assumed to accumulate in stem cells over time and their ability to withstand this damage and maintain tissue homeostasis is the key dete......

JIF:5.215

P21-Activated Kinase 4 Pak4 Maintains Embryonic Stem Cell Pluripotency via Akt Activation

期刊: STEM CELLS, 2022; 40 (10)

Exploiting the pluripotent properties of embryonic stem cells (ESCs) holds great promise for regenerative medicine. Nevertheless, directing ESC differ......

JIF:5.215

beta-Arrestin 2 and Epac2 Cooperatively Mediate DRD1-Stimulated Proliferation of Human Neural Stem Cells and Growth of Human Cerebral Organoids

期刊: STEM CELLS, 2022; 40 (9)

G-protein-coupled receptors (GPCRs) reportedly relay specific signals, such as dopamine and serotonin, to regulate neurogenic processes although the u......

JIF:5.215

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