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Role of IL-22 in intestinal microenvironment and potential targeted therapy through diet

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (2)

IL-22 is a type 2 receptor cytokine in IL-10 family. IL-22 is usually secreted by innate and adaptive immune cells and takes its effects on non-hemato......

Reduction in experimental autoimmune thyroiditis by IgG Fc fragments bearing regRF epitopes

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (1)

Previously, we identified a new immunoregulatory factor, the production of which provides rats with resistance to certain experimental autoimmune dise......

In silico design and evaluation of a novel mRNA vaccine against BK virus: a reverse vaccinology approach

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (3)

Human polyomavirus type 1, or BK virus (BKV), is a ubiquitous pathogen belonging to the polyomaviridae family mostly known for causing BKV-associated ......

Potential role of EBV and Toll-like receptor 9 ligand in patients with systemic lupus erythematosus

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (5)

SLE is a multisystem autoimmune disease characterized by multiple immunological abnormalities including production of autoantibodies. While the etiolo......

Circulating anti-hypothalamus antibodies in celiac patients: tissue transglutaminase friend or foe?

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (6)

Celiac disease (CD) is an autoimmune disease with inflammatory characteristics, having a condition of chronic malabsorption, affecting approximately 1......

Serum soluble LYVE1 is a promising non-invasive biomarker of renal fibrosis: a population-based retrospective cross-sectional study

期刊: IMMUNOLOGIC RESEARCH, 2023; ()

Diagnosis of renal fibrosis can only be verified by kidney biopsy, but biomarkers for non-invasive evaluation remain unsatisfactory. Patients with fib......

IDO blockade negatively regulates the CTLA-4 signaling in breast cancer cells

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (5)

Cancer is classified into metabolic and/or genetic disorders; notably, the tryptophan catabolism pathway is vital in different cancer types. Here, we ......

Conventional Tregs in treatment-naïve rheumatoid arthritis are deficient in suppressive function with an increase in percentage of CXCR3 and CCR6 expressing Tregs

期刊: IMMUNOLOGIC RESEARCH, 2023; ()

In rheumatoid arthritis (RA), immune homeostasis is maintained by T regulatory cells (Tregs) that in an inflammatory milieu can change towards T-helpe......

An assessment of the strategy and status of COVID-19 vaccination in India

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (4)

The COVID-19 disease continues to cause devastation for almost 3 years of its identification. India is one of the leading countries to set clinical tr......

Th17 cytokines and factors modulating their activity in patients with pernicious anemia

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (6)

The effects of specific cytokines produced by T cell subsets (such as Th1, Th2, and newly discovered Th17, Treg, Tfh, or Th22) are diverse, depending ......

Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients

期刊: IMMUNOLOGIC RESEARCH, 2023; ()

The detection of cryoglobulins (CG) used to diagnose cryoglobulinemic vasculitis requires strict adherence to protocol, with emphasis on the preanalyt......

An epicutaneous therapeutic pollen-allergen extract delivery system in an allergic rhinitis mouse model: based on allergen loading on DC-specific aptamers conjugated nanogolds

期刊: IMMUNOLOGIC RESEARCH, 2023; ()

BackgroundGold nanoparticles (GNPs) have previously been suggested as appropriate carriers for allergen-specific immunotherapy (AIT). In this study, w......

Lower expression of NINJ1 (Ninjurin 1), a mediator of plasma membrane rupture, is associated with advanced disease and worse prognosis in serous ovarian cancer

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (1)

Gasdermin proteins (GSDMs) form pores in cell membranes upon various stimuli, leading to the release of certain proinflammatory molecules such as IL-1......

Functions of MAP3Ks in antiviral immunity

期刊: IMMUNOLOGIC RESEARCH, 2023; 71 (6)

Immune signal transduction is crucial to the body's defense against viral infection. Recognition of pathogen-associated molecular patterns by pattern ......

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