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Advances in Circular RNA and Its Applications

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (6)

Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, un......

JIF:3.576

SJMHE1 protects against excessive iodine-induced pyroptosis in human thyroid follicular epithelial cells through a toll-like receptor 2-dependent pathway

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (4)

To elucidate the effect of Schistosoma japonicum peptide (SJMHE1) on pyroptosis in thyroid follicular epithelial cells (TFCs) induced by excessive iod......

JIF:3.576

Immune Reconstitution in Pediatric Aplastic Anemia after Allogeneic Hematopoietic Stem-cell Transplantation

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

Background: Previous studies had revealed that immune reconstitution (IR) after allogeneic hematopoietic stem-cell transplantation (allo-HSCT) affecte......

JIF:3.576

The role of circular RNA in Diabetic Nephropathy

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

Diabetic nephropathy (DKD) is the most common chronic microvascular complication of diabetes. About 20%-40% of diabetics develop DKD, which eventually......

JIF:3.576

Hsa_circRNA_0040462: a sensor of cells' response to CAP treatment with double-edged roles on breast cancer malignancy

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (4)

Cold atmospheric plasma (CAP) represents a novel onco-therapeutic approach that has demonstrated its efficacy in many types of tumors. The efficacy of......

JIF:3.576

SIRT1: A Novel Protective Molecule in Pre-eclampsia

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (6)

Pre-eclampsia is a severe pregnant complication, mainly characterized by insufficient trophoblast invasion, impaired uterine spiral artery remodeling,......

JIF:3.576

Oridonin represses epithelial-mesenchymal transition and angiogenesis of thyroid cancer via downregulating JAK2/STAT3 signaling

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (6)

Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens, has been reported to exert anticancer activity in various cancers. However, the mo......

JIF:3.576

Bioinformatic Analysis Identifying PSMB 1/2/3/4/6/8/9/10 as Prognostic Indicators in Clear Cell Renal Cell Carcinoma

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (5)

Renal cancer incidence has been increasing across the world, clear cell renal cell carcinoma (ccRCC) represents the major subtype of renal cancer. The......

JIF:3.576

Cell death mechanisms induced by synergistic effects of halofuginone and artemisinin in colorectal cancer cells

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (1)

Our previous study found that the combination of halofuginone (HF) and artemisinin (ATS) synergistically arrest colorectal cancer (CRC) cells at the G......

JIF:3.576

Expression Landscape and Functional Roles of HOXA4 and HOXA5 in Lung Adenocarcinoma

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (3)

Background: The role of HOXA family genes in the occurrence and progression of a variety of human cancers has been scatteredly reported. However, ther......

JIF:3.576

Changes of Migration, Immunoregulation and Osteogenic Differentiation of Mesenchymal Stem Cells in Different Stages of Inflammation

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (1)

Bone infection has always been the focus of orthopedic research. Mesenchymal stem cells (MSCs) are the natural progenitors of osteoblasts, and the pro......

JIF:3.576

Differential lipidomics of HK-2 cells and exosomes under high glucose stimulation

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (2)

Abnormal cellular lipid metabolism has a very important role in the occurrence and progression of diabetic kidney disease (DKD). However, the lipid co......

JIF:3.576

Investigation and Validation of Molecular Characteristics of Endometrium in Recurrent Miscarriage and Unexplained Infertility from a Transcriptomic Perspective

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (3)

Recurrent miscarriage (RM) and unexplained infertility (UI) are gordian knots in reproductive medicine, which are troubling many patients, doctors, an......

JIF:3.576

Abnormally decreased renal Klotho is linked to reticulum-associated in mice

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (2)

Aim: Endoplasmic reticulum-associated degradation (ERAD), which involves degradation of improperly folded proteins retained in the ER, is implicated i......

JIF:3.576

Exosomes with FOXP3 from gene-modified dendritic cells ameliorate the development of EAE by regulating the balance of Th/Treg

期刊: INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022; 19 (8)

Objective: To investigate the efficiency and potential mechanisms of exosomes from dendritic cells (DCs) transfected with Forkhead box protein P3 (FOX......

JIF:3.576

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