期刊: CANCER SCIENCE, 2021; 112 (9)
Mutated KRAS promotes the activation of the MAPK pathway and the progression of colorectal cancer (CRC) cells. Aberrant activation of the PI3K pathway......
期刊: CANCER SCIENCE, 2021; 112 (6)
The tumor microenvironment, comprised of tumor cells and tumor-infiltrating immune cells, is closely associated with the clinical outcome of clear cel......
期刊: CANCER SCIENCE, 2021; 112 (7)
Traditional histopathology performed by pathologists by the naked eye is insufficient for accurate and efficient diagnosis of bladder cancer (BCa). We......
期刊: CANCER SCIENCE, 2021; 112 (7)
The efficacy and side effects of the second-time humanized CD19 chimeric antigen receptor (CD19-CAR) T-cell therapy after unsuccessful first-time anti......
期刊: CANCER SCIENCE, 2021; 112 (9)
Tumor-induced angiogenesis is important for further progression of solid tumors. The initiation of tumor angiogenesis is dictated by a shift in the ba......
期刊: CANCER SCIENCE, 2021; 112 (9)
The long reads of Nanopore sequencing permit accurate transcript assembly and ease in discovering novel transcripts with potentially important functio......
期刊: CANCER SCIENCE, 2021; 112 (8)
Protein kinase B (AKT) hyperactivation and de novo lipogenesis are both common in tumor progression. Sterol regulatory element-binding protein 1 (SREB......
期刊: CANCER SCIENCE, 2021; 112 (8)
Although immune checkpoint inhibitors (ICIs) have achieved unprecedented success in dMMR tumors, pMMR tumors accounting for 85% of colorectal cancer (......
期刊: CANCER SCIENCE, 2021; 112 (9)
Renal carcinoma shows a high risk of invasion and metastasis without effective treatment. Herein, we developed a chitosan (CS) nanoparticle-mediated D......
期刊: CANCER SCIENCE, 2021; 112 (8)
The two principal histological types of primary liver cancers, hepatocellular carcinoma (HCC) and cholangiocarcinoma, can coexist within a tumor, comp......
期刊: CANCER SCIENCE, 2021; 112 (8)
Skp2 is overexpressed in multiple cancers and plays a critical role in tumor development through ubiquitin/proteasome-dependent degradation of its sub......
期刊: CANCER SCIENCE, 2021; 112 (9)
Necroptosis is an alternative form of programmed cell death that generally occurs under apoptosis-deficient conditions. Our previous work showed that ......
期刊: CANCER SCIENCE, 2021; 112 (9)
Despite considerable efforts in the detection and treatment of gastric cancer (GC), the underlying mechanism of the progression of GC remains unknown.......
期刊: CANCER SCIENCE, 2021; 112 (6)
Arecoline, the main alkaloid of areca nut, is well known for its role in inducing submucosal fibrosis and oral squamous cell carcinoma (OSCC), however......
期刊: CANCER SCIENCE, 2021; 112 (6)
Single-nucleotide polymorphisms (SNP) and long non-coding RNAs (lncRNAs) have been involved in the process of lung cancer. Following clues given by lu......