期刊: NATURE MEDICINE, 2023; 29 (5)
The lack of multi-omics cancer datasets with extensive follow-up information hinders the identification of accurate biomarkers of clinical outcome. In......
期刊: NATURE MEDICINE, 2023; 29 (8)
We investigated whether human preferences hold the potential to improve diagnostic artificial intelligence (AI)-based decision support using skin canc......
Pre-exposure prophylaxis (PrEP) with tenofovir (TFV) disoproxil fumarate and emtricitabine administered orally daily is effective in preventing human ......
期刊: NATURE MEDICINE, 2023; 29 (5)
Erythropoietin (Epo) is the master regulator of erythropoiesis and oxygen homeostasis. Despite its physiological importance, the molecular and genomic......
External comparator arms should be used when investigating novel therapies for gastrointestinal stromal tumor and other rare tumors to facilitate drug......
期刊: NATURE MEDICINE, 2023; 29 (3)
Despite scientific evidence originating from two patients published to date that CCR5 Delta 32/Delta 32 hematopoietic stem cell transplantation (HSCT)......
期刊: NATURE MEDICINE, 2023; 29 (3)
A deep-learning algorithm was developed to identify skin lesions caused by the mpox virus and was then implemented in a web-based app designed for pat......
期刊: NATURE MEDICINE, 2023; 29 (3)
A flexible and compact database containing rare variant genotypes and phenotypes of 77,539 participants sequenced by the 100,000 Genomes Project enabl......
期刊: NATURE MEDICINE, 2023; 29 (7)
While over 100 genes have been associated with autism, little is known about the prevalence of variants affecting them in individuals without a diagno......
期刊: NATURE MEDICINE, 2023; 29 (6)
A multi-ancestry genetic meta-analysis identifies 12 new loci associated with preeclampsia and gestational hypertension and proposes the integration o......
期刊: NATURE MEDICINE, 2023; 29 (6)
Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate its treatment. AEF0117, the first of a new pharmacological cl......
期刊: NATURE MEDICINE, 2023; 29 (5)
Neuroblastomas harbor ALK aberrations clinically resistant to crizotinib yet sensitive pre-clinically to the third-generation ALK inhibitor lorlatinib......
期刊: NATURE MEDICINE, 2023; 29 (7)
Depression is a common psychiatric disorder and a leading cause of disability worldwide. Here we conducted a genome-wide association study meta-analys......
Autologous hematopoietic stem cell transplantation (ASCT) improves survival in multiple myeloma (MM). However, many individuals are unable to collect ......