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SOX14 hypermethylation as a tumour biomarker in cervical cancer

期刊: BMC CANCER, 2021; 21 (1)

Background The association between SOX14 and cancer has been reported. The aim of this study was to identify and validate the potential value of SOX14......

Associations between female lung cancer risk and sex steroid hormones: a systematic review and meta-analysis of the worldwide epidemiological evidence on endogenous and exogenous sex steroid hormones

期刊: BMC CANCER, 2021; 21 (1)

Background Published findings suggest sex differences in lung cancer risk and a potential role for sex steroid hormones. Our aim was to perform a meta......

A novel risk score system for prognostic evaluation in adenocarcinoma of the oesophagogastric junction: a large population study from the SEER database and our center

期刊: BMC CANCER, 2021; 21 (1)

Background The incidence rate of adenocarcinoma of the oesophagogastric junction (AEG) has significantly increased over the past decades, with a stead......

Modified FOLFIRINOX versus gemcitabine plus oxaliplatin as first-line chemotherapy for patients with locally advanced or metastatic cholangiocarcinoma: a retrospective comparative study

期刊: BMC CANCER, 2021; 21 (1)

BackgroundGemcitabine plus platinum as the first-line chemotherapy for cholangiocarcinoma (CCA) has limited efficacy. The aim of this study was to eva......

Nomogram predict relapse-free survival of patients with thymic epithelial tumors after surgery

期刊: BMC CANCER, 2021; 21 (1)

Background Hematological indicators and clinical characteristics play an important role in the evaluation of the progression and prognosis of thymic e......

A phase I/II clinical trial on the efficacy and safety of NKT cells combined with gefitinib for advanced EGFR-mutated non-small-cell lung cancer

期刊: BMC CANCER, 2021; 21 (1)

Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib, have achieved good efficacy in EGFR mutation-p......

Identification of prognostic immune-related gene signature associated with tumor microenvironment of colorectal cancer

期刊: BMC CANCER, 2021; 21 (1)

Background The tumor microenvironment (TME) has significantly correlation with tumor occurrence and prognosis. Our study aimed to identify the prognos......

Association between preoperative serum albumin and prognosis in patients with adrenocortical carcinoma after primary resection: a retrospective study

期刊: BMC CANCER, 2021; 21 (1)

Background Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with a poor prognosis. Given the limited treatment options, prognostic a......

Long non-coding RNAs HERH-1 and HERH-4 facilitate cyclin A2 expression and accelerate cell cycle progression in advanced hepatocellular carcinoma

期刊: BMC CANCER, 2021; 21 (1)

Background The advanced hepatocellular carcinoma (HCC), such as the recurrent tumor after liver transplantation (LT), is an obstacle of HCC treatment.......

A novel tool for predicting the survival of endoprosthesis used for reconstruction of the knee following tumor resection: a retrospective cohort study

期刊: BMC CANCER, 2021; 21 (1)

Background Prosthesis-related complications, after knee reconstruction with endoprosthesis during operation for tumors around the knee, remain an unre......

Identification of the potential novel biomarkers as susceptibility gene for Wilms tumor

期刊: BMC CANCER, 2021; 21 (1)

BackgroundWilms tumor (WT) is the most common malignant renal tumor in children. The aim of this study was to identify potential susceptibility gene o......

Association of ST6GAL1 and CYP19A1 polymorphisms in the 3 '-UTR with astrocytoma risk and prognosis in a Chinese Han population

期刊: BMC CANCER, 2021; 21 (1)

Background Astrocytoma is a common type of central nervous system tumor. In this study, we investigated the correlation between ST6GAL1 and CYP19A1 po......

Prognostic value of the extent of lymphadenectomy for esophageal cancer-specific survival among T1 patients

期刊: BMC CANCER, 2021; 21 (1)

BackgroundClinically, there are no clear guidelines on the extent of lymphadenectomy in patients with T1 esophageal cancer. Studying the minimum numbe......

Immunological effect of irreversible electroporation on hepatocellular carcinoma

期刊: BMC CANCER, 2021; 21 (1)

BackgroundThis study intends to investigate the immunological effects of tumor ablation with irreversible electroporation (IRE).MethodsWe evaluated th......

Genetic alteration of Chinese patients with rectal mucosal melanoma

期刊: BMC CANCER, 2021; 21 (1)

BackgroundRectal mucosal melanoma (RMM) is a rare and highly aggressive disease with a poor prognosis. Due to the rarity of RMM, there are few studies......

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