期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (4)
Identification of cancer-related genes is helpful for understanding the pathogenesis of cancer, developing targeted drugs and creating new diagnostic ......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (3)
Large quantity of variants of uncertain significance (VUS) has been identified in cancer predisposition genes, but classification of VUS remains a big......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (6)
Molecular biology has revealed that complex life phenomena can be treated as the result of many gene interactions. Investigating these interactions an......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (6)
Single-cell ribonucleic acid (RNA)-sequencing (scRNA-seq) data analysis refers to the use of appropriate methods to analyze the dataset generated by R......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (3)
Background Nonsmall cell lung cancer (NSCLC) ranks first among global cancer-related deaths. Despite the emergence of various immunological and target......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (3)
The way of co-administration of drugs is a sensible strategy for treating complex diseases efficiently. Because of existing massive unknown interactio......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (4)
With the rapid advancement in sequencing technologies, the concept of omics has revolutionized our understanding of cellular behaviors. Conventional o......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (5)
In the past decade, digital PCR (dPCR), as a new nucleic acid absolute quantification technology, has been widely used in clinical research. dPCR does......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (2)
We propose the hierarchical Projective Adaptive Resonance Theory (PART) algorithm for classification of gene expression data. This algorithm is realiz......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (3)
Triple-negative breast cancer (TNBC) is the breast cancer subtype with the highest fatality rate, and it seriously threatens women's health. Recent st......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (5)
Transcription factors are important cellular components of the process of gene expression control. Transcription factor binding sites are locations wh......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (4)
Cancer is generally caused by genetic mutations, and differentially expressed genes are closely associated with genetic mutations. Therefore, mutated ......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (2)
Breast cancer is a kind of malignant tumor that occurs in breast tissue, which is the most common cancer in women. Cellular metabolism is a critical d......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (5)
Identification and classification of enhancers are highly significant because they play crucial roles in controlling gene transcription. Recently, sev......
期刊： BRIEFINGS IN FUNCTIONAL GENOMICS, 2022; 21 (6)
The elevated levels of inflammatory cytokines have attracted much attention during the treatment of COVID-19 patients. The conclusions of current obse......
