期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a tenacious pathogen that has latently infected one third of the world'......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
Rheumatoid arthritis (RA) is a chronic autoimmune disorder affecting joints with a hallmark of autoantibody production. Mannan-enhanced collagen type ......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
CRISPR-Cas systems are an immune defense mechanism that is widespread in archaea and bacteria against invasive phages or foreign genetic elements. In ......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
Proteolysis targeting chimeras (PROTACs) technology has emerged as a novel therapeutic paradigm in recent years. PROTACs are heterobifunctional molecu......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
MicroRNA-22 (miR-22) was suggested to be important for type 2 diabetes but its functions for this disease remained unclear. Recombinant adeno-associat......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
Extrachromosomal circular DNA (eccDNA) has been shown to play an important role in the amplification of tumor genes and the maintenance of intra-tumor......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
Since the first monoclonal antibody drug, muromonab-CD3, was approved for marketing in 1986, 165 antibody drugs have been approved or are under regula......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
Intracellular vesicle trafficking is the fundamental process to maintain the homeostasis of membrane-enclosed organelles in eukaryotic cells. These or......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
COVID-19 caused by SARS-CoV-2 has created formidable damage to public health and market economy. Currently, SARS-CoV-2 variants has exacerbated the tr......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor, human epidermal growth factor receptor 2 and progesterone ......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
The discovery and development of the CRISPR/Cas system is a milestone in precise medicine. CRISPR/Cas nucleases, base-editing (BE) and prime-editing (......
期刊： MOLECULAR BIOMEDICINE, 2022; 3 (1)
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading globally and continues to rage, posing a s......
