期刊: CANCER GENE THERAPY, 2022; 29 (1)
microRNAs (miRNAs) have been revealed to participate in some oral cancers and are proved to be effective. In the present study, we tried to explore th......
期刊: CANCER GENE THERAPY, 2022; 29 (2)
Major histocompatibility complex class II (MHC II) is important for the adaptive immune response because MHC II presents processed antigens to a clust......
期刊: CANCER GENE THERAPY, 2022; 29 (5)
Overexpression of O-6-methylguanine DNA methyltransferase (MGMT) contributes to resistance to chemo-radiation therapy (CRT) in brain tumors. We previo......
期刊: CANCER GENE THERAPY, 2022; 29 (6)
CDK4/6 inhibitors significantly prolong progression-free survival in patients with advanced hormone receptor-positive (HR+) HER2-negative breast cance......
期刊: CANCER GENE THERAPY, 2022; 29 (7)
Lung carcinoma is the main reason for cancer-associated deaths in the world. In a previous study, FCH domain only 1 (FCHo1) which is managed by protei......
期刊: CANCER GENE THERAPY, 2022; 29 (1)
Significantly high-expressed circFLNA has been found in various cancer cell lines, but not in lung cancer. Therefore, this study aimed to explore the ......
期刊: CANCER GENE THERAPY, 2022; 29 (3-4)
Long non-coding RNAs (lncRNAs) were recently recognized to vitally function in a variety of cancer cellular events, including epithelial-mesenchymal t......
期刊: CANCER GENE THERAPY, 2022; 29 (6)
Immunotherapeutic strategies that combine oncolytic virus (OV) and immune checkpoint inhibitors have the potential to overcome treatment resistance in......
期刊: CANCER GENE THERAPY, 2022; 29 (7)
Engineered T-cell therapies have proven to be successful in cancer and their clinical effectiveness is directly correlated with the infused T-cell dif......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
DNA methylation, a major biological process regulating the transcription, contributes to the pathophysiology of hematologic malignancies, and hypometh......
期刊: CANCER GENE THERAPY, 2022; 29 (6)
Multikinase inhibitors, such as sorafenib, are used for the treatment of advanced carcinomas but the response shows limited efficacy or varies a lot w......
期刊: CANCER GENE THERAPY, 2022; 29 (7)
Aberrant Notch signaling is implicated in breast cancer progression, and recent studies have demonstrated links between the Notch pathway components N......
期刊: CANCER GENE THERAPY, 2022; 29 (8-9)
Autophagy is the predominant self-eating catabolic pathway activated in response to nutrient starvation and hypoxia within the microenvironment of var......
期刊: CANCER GENE THERAPY, 2022; 29 (10)
One of the greatest challenges in the treatment of cancer is tumor heterogeneity which results in differential responses to chemotherapy and drugs tha......
期刊: CANCER GENE THERAPY, 2022; 29 (11)
Drug resistance is a key factor in the treatment failure of acute myeloid leukemia (AML). Nuclear factor E2-related factor 2 (Nrf2) plays a crucial ro......