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Prevalence and risk factors of relapse in patients with ANCA-associated vasculitis receiving cyclophosphamide induction: a systematic review and meta-analysis of large observational studies

期刊: RHEUMATOLOGY, 2021; 60 (3)

Background. Clinical relapses are common in patients with ANCA-associated vasculitis (AAV). The aim of this systematic review was to estimate time-poi......

Study of miRNA interactome in active rheumatoid arthritis patients reveals key pathogenic roles of dysbiosis in the infection-immune network

期刊: RHEUMATOLOGY, 2021; 60 (3)

Objectives. To characterize serum microRNA (miR) and the miR interactome of active RA patients in RA aetiology and pathogenesis. Methods. The differen......

The causal effect of interleukin-17 on the risk of psoriatic arthritis: a Mendelian randomization study

期刊: RHEUMATOLOGY, 2021; 60 (4)

Objective. To determine causal associations between genetically predicted TNF-alpha, IL-12p70 and IL-17 levels and risk of PsA. Methods. The publicly ......

Clinical features, treatments and outcomes of calcinosis in adult patients with dermatomyositis: a single cohort study

期刊: RHEUMATOLOGY, 2021; 60 (6)

Objective. The occurrence of calcinosis cutis as a clinical feature of dermatomyositis in adult patients is not well understood. Cohort studies of adu......

Post-translational modifications in T cells in systemic erythematosus lupus

期刊: RHEUMATOLOGY, 2021; 60 (6)

Systemic erythematosus lupus (SLE) is a classic autoimmune disease characterized by multiple autoantibodies and immune-mediated tissue damage. The aet......

Increased expression of interleukin-21-inducible genes in minor salivary glands are associated with primary Sjogren's syndrome disease characteristics

期刊: RHEUMATOLOGY, 2021; 60 (6)

Objective. To determine the upregulation of IL-21-inducible genes in minor salivary glands (MSGs) in 28 primary SS (pSS) patients and 12 non-pSS subje......

Circulating adiponectin levels and systemic lupus erythematosus: a two-sample Mendelian randomization study

期刊: RHEUMATOLOGY, 2021; 60 (2)

Objectives. Several studies have reported increased serum/plasma adiponectin levels in SLE patients. This study was performed to estimate the causal e......

Quantitative and semi-quantitative assessment of synovitis on MRI and the relationship with symptoms in symptomatic knee osteoarthritis

期刊: RHEUMATOLOGY, 2021; 60 (4)

Objectives. Synovitis in symptomatic knee OA (KOA) is common and is associated with joint symptoms. Optimal synovial measurement on MRI is, however, u......

Untargeted lipidomics reveals specific lipid abnormalities in Sjogren's syndrome

期刊: RHEUMATOLOGY, 2021; 60 (3)

Objective: The relationship between serum lipid variations in SS and healthy controls was investigated to identify potential predictive lipid biomarke......

Increased risk of rheumatoid arthritis among patients with endometriosis: a nationwide population-based cohort study

期刊: RHEUMATOLOGY, 2021; 60 (7)

Objectives: Autoimmunity may play a role in endometriosis. The association between endometriosis and RA remains unknown. This study was conducted to i......

Causal association of adipokines with osteoarthritis: a Mendelian randomization study

期刊: RHEUMATOLOGY, 2021; 60 (6)

Objective. This two-sample Mendelian randomization study aimed to delve into the effects of genetically predicted adipokine levels on OA. Methods. Sum......

UPLC-MS based plasma metabolomics and lipidomics reveal alterations associated with IgG4-related disease

期刊: RHEUMATOLOGY, 2021; 60 (7)

Objective. The pathogenesis of IgG4-related disease (IgG4-RD) remains unclear. Metabolomic profiling of IgG4RD patients offers an opportunity to ident......

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