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Pathological complete response to neoadjuvant ceritinib of a crizotinib-resistant, stage IIIB non-small cell lung cancer with ALK rearrangement: A case report

期刊: THORACIC CANCER, 2021; 12 (14)

The treatment of stage IIIB non-small cell lung cancer (NSCLC) is complicated, the best strategy is chosen individually and surgery is usually not rec......

Overexpression of BCCIP predicts an unfavorable prognosis and promotes the proliferation and migration of lung adenocarcinoma

期刊: THORACIC CANCER, 2021; 12 (17)

Background Lung cancer accounts for the highest rate of cancer-related diagnosis and mortality. Lung adenocarcinoma (LUAD) is the most common histopat......

Clinical characteristics of paraneoplastic neurological syndrome related to different pathological lung cancers

期刊: THORACIC CANCER, 2021; 12 (16)

Background Paraneoplastic syndrome is a distant effect caused by malignant tumors, which is related to the production of cellular immune response. The......

LncRNA SGMS1-AS1 regulates lung adenocarcinoma cell proliferation, migration, invasion, and EMT progression via miR-106a-5p/MYLI9 axis

期刊: THORACIC CANCER, 2021; 12 (14)

Background: Lung cancer mainly includes non-small cell lung cancer (NSCLC). Lung adenocarcinoma (LUAD) is the main subtype of NSCLC. Long non-coding R......

miR-21-5p/SMAD7 axis promotes the progress of lung cancer

期刊: THORACIC CANCER, 2021; 12 (17)

Background Lung cancer is one of the most common malignant tumors threatening human health. The aim of this study was to investigate the function of m......

Potential role for the tumor suppressor CYLD in brain and notochord development

期刊: THORACIC CANCER, 2021; 12 (12)

Background The cylindromatosis (CYLD) tumor suppressor is a microtubule-associated deubiquitinase that plays a critical role in the regulation of cell......

T-cell response to phytohemagglutinin in the interferon-gamma release assay as a potential biomarker for the response to immune checkpoint inhibitors in patients with non-small cell lung cancer

期刊: THORACIC CANCER, 2021; 12 (11)

Background Immune checkpoint inhibitors are a standard treatment for advanced lung cancer, although it remains important to identify biomarkers that c......

Ultrathin bronchoscope combined with virtual bronchoscopic navigation and endobronchial ultrasound for the diagnosis of peripheral pulmonary lesions with or without fluoroscopy: A randomized trial

期刊: THORACIC CANCER, 2021; 12 (12)

Background Transbronchial lung biopsy (TBLB) is usually performed to obtain a definitive diagnosis for peripheral pulmonary lesions (PPLs). Ultrathin ......

Neoantigen load as a prognostic and predictive marker for stage II/III non-small cell lung cancer in Chinese patients

期刊: THORACIC CANCER, 2021; 12 (15)

Background The prognosis for patients with stage II/III non-small cell lung cancer (NSCLC) is unsatisfactory, even after complete tumor resection and ......

Time-varying effect of sex on prognosis of lung adenocarcinoma surgical patients in China

期刊: THORACIC CANCER, 2021; 12 (11)

Background Little is known about the prognostic advantage of sex for pulmonary adenocarcinoma among Chinese patients. In this study, we aimed to inves......

Primary resistance to alectinib in a patient with STRN-ALK-positive non-small cell lung cancer: A case report

期刊: THORACIC CANCER, 2021; 12 (12)

Anaplastic lymphoma kinase (ALK) rearrangements are drivers of a subset of non-small cell lung cancer (NSCLC). The rapid progression of ALK inhibitors......

Circular RNA circLDB2 functions as a competing endogenous RNA to suppress development and promote cisplatin sensitivity in non-squamous non-small cell lung cancer

期刊: THORACIC CANCER, 2021; 12 (13)

Background Circular RNAs (circRNAs) are covalently closed RNAs and are implicated in the development of non-small cell lung cancer (NSCLC). Here, we i......

Concurrent chemoradiotherapy versus radiotherapy alone for patients with locally advanced esophageal squamous cell carcinoma in the era of intensity modulated radiotherapy: a propensity score-matched analysis

期刊: THORACIC CANCER, 2021; 12 (12)

Background To investigate the survival benefit of concurrent chemoradiotherapy (CCRT) for patients with locally advanced esophageal squamous cell carc......

tRNA-derived fragments: tRF-Gly-CCC-046, tRF-Tyr-GTA-010 and tRF-Pro-TGG-001 as novel diagnostic biomarkers for breast cancer

期刊: THORACIC CANCER, 2021; 12 (17)

Background tRNA-derived fragments (tRFs) have been found to play a regulatory role in the occurrence and development of many tumors. The aim of this s......

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